Familial hemiplegic migraine type 2 (FHM2) causes a malfunction of astrocytes in the cingulate cortex. Manipulating astrocytes in the cingulate cortex reversed the disfunction, preventing an increase in migraine-like symptoms in mice carrying the FHM2 defect.
A new study has identified rare genetic variation in the Thorase protein that causes the breakdown of receptors at the connections between neurons in the brain. The anti-epilepsy drug perampanel can help reverse anti-social behaviors linked to schizophrenia that are associated with this genetic variation.
A new paper offers an overview as to how neurons communicate with one another.