FeaturedGeneticsNeuroscience·March 28, 2021·3 min readEat Me: The Cell Signal of DeathA nuclear fragment protein activates Xkr4 to display an "eat me" signal to phagocytes.Read More
FeaturedGeneticsNeuroscience·July 24, 2020·4 min readNeurons Are Genetically Programmed to Have Long LivesResearchers have identified a mechanism triggered at neuron birth to intrinsically decrease apoptosis. When the genetic regulation is halted, continuous neuronal survival is disrupted, leading to a decrease in animal survival.Read More
FeaturedGeneticsNeuroscience·April 10, 2020·4 min readMapping SARS-CoV-2 active proteins and how COVID-19 spreads throughout the bodyResearchers have mapped the interaction between SARS-CoV-2 proteins and human cells, showing which proteins are being activated and deactivated by coronavirus. The findings reveal how the virus can spread through the human body.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·March 11, 2020·3 min read‘Zombie’ brain cells develop into working neuronsGenetically preventing apoptosis during brain growth allows 'zombie' cells to develop into functioning neurons.Read More
FeaturedNeuroscience·February 3, 2020·3 min readBirth timing may affect brain developmentEarly birth prompted apoptosis to begin a day early, but delaying the birth did not alter when cell death began to occur. The study suggests birth time has an important and previously unrecognized effect on brain development.Read More
FeaturedGeneticsNeurologyNeuroscience·January 15, 2020·3 min readInflammation a “game changer” as cellular death dance discoveredTNFR1 receptors arrange themselves into clusters, joining together trimers and making oligomers that create a pro-inflammatory response observed in a variety of diseases.Read More
FeaturedNeurologyNeuroscience·December 9, 2019·2 min readEating more ketones may fight against Alzheimer’s diseaseIncreasing SIRT3 levels with a ketone rich diet may help protect GABAergic interneurons and delay the onset of Alzheimer's disease.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·September 13, 2019·4 min readDiscovery concerning the nervous system overturns a previous theoryRather than having an equal chance of survival, cell death appears to be controlled by a mechanism that filters our the less fit cells.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·September 4, 2019·4 min readNew insight into motor neuron death mechanisms could be a step toward ALS treatmentWhen a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.Read More
FeaturedNeurologyNeuroscience·August 29, 2019·4 min readLack of oxygen doesn’t kill infant brain cells, as previously thoughtA lack of oxygen as a result of preterm birth does not cause hippocampal neurons to die but does impair hippocampal development. Hypoxia causes hippocampal cells to fail to mature normally, causing a reduction in long-term potentiation and impaired learning.Read More
FeaturedNeuroscience·August 22, 2019·2 min readCell suicide could hold key for brain health and food securityA new study into human and plant cell apoptosis could provide new avenues for the development of treatments for neurodegenerative diseases, and help develop disease-resistant plants.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience ArticlesPsychology·August 9, 2019·3 min readHow chronic stress causes brain damageChronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.Read More