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Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

Neuroscience News
Researchers use SWITCH technology to label amyloid plaques in mouse models of Alzheimer's disease so they could be imaged in fine detail at different ages. They were consistently able to see the plaques first emerged in deep brain structures and tracked circuits, such as the Papez memory circuit, to spread throughout the brain as the animal aged.... Read More...
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Why visual stimulation may work in fight against Alzheimer’s: Mouse study

Neuroscience News
Inducing gamma oscillations with visual stimulation via a process known as gamma entrainment using sensory stimuli, or GENUS, was shown to reduce amyloid plaques and phosphorylated tau in mouse models of dementia. Providing GENUS daily during the early stages of neurodegeneration helps preserve neural and synaptic density across multiple brain areas and improves cognitive performance for learning and spatial memory tasks.... Read More...
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Sleep Problems May Be An Early Sign of Alzheimer’s

Neuroscience News
A new study links sleep problems with increased biomarkers for Alzheimer's disease. Researchers discovered those who report low sleep quality, daytime sleepiness and other sleep problems had elevated levels of Alzheimer's related biomarkers in their spinal fluid than those who reported no sleep problems. However, no abnormalities were found in the spinal fluid of people with obstructive sleep apnea.... Read More...
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