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Alzheimer’s disease

·May 14, 2024·5 min read

New Technique Reveals Rapid Aging in Alzheimer’s Brain Cells

Neuroengineers discovered that certain brain cells age faster than others, particularly in Alzheimer’s patients. Using a new technique called MUSIC, they identified distinct aging patterns in brain cells and sex-specific differences in aging.

Featured Genetics Neurology Neuroscience

·May 14, 2024·6 min read

Mini-Brains from Stem Cells Provide Hope for Alzheimer’s Diagnosis

Researchers developed tiny "mini-brains" from stem cells to help diagnose and treat Alzheimer’s disease. These mini-brains, created from human blood, accurately reflect the pathology of Alzheimer’s on a smaller scale. This innovative technology could revolutionize healthcare, especially for remote communities, by providing a simpler way to diagnose neurological conditions.

Featured Genetics Neurology Neuroscience

·May 13, 2024·4 min read

tRNA Fragments Linked to Alzheimer’s

A new study identifies a crucial factor in brain aging and Alzheimer's disease—the accumulation of Glu-5’tsRNA-CTC in neuron mitochondria. This small RNA fragment disrupts mitochondrial protein synthesis and cristae structure, accelerating cognitive decline and Alzheimer’s pathology.

Featured Neurology Neuroscience

·May 8, 2024·5 min read

Youth-Onset Diabetes Linked to Higher Alzheimer’s Risk

Researchers identified a potential early Alzheimer's disease (AD) risk in young people with diabetes. The study discovered blood biomarkers and amyloid protein accumulations typical of AD in individuals diagnosed with diabetes during childhood or adolescence.

Featured Genetics Neurology Neuroscience

·May 6, 2024·5 min read

APOE4 Gene Doubles Up Alzheimer’s Risk

A novel study sheds new light on the link between the APOE4 gene and Alzheimer’s disease. The study reveals that over 95% of individuals over 65 who have two copies of the APOE4 gene exhibit biological markers of Alzheimer's in the brain or through cerebrospinal fluid and PET scans.

Featured Genetics Neurology Neuroscience

·April 29, 2024·4 min read

High-Fat Diet Linked to Alzheimer’s Through Molecular Changes

A new study uncovered how diets high in saturated fats contribute to the development of Alzheimer’s disease by affecting crucial molecular markers in the brain and blood. The research utilized mouse models to investigate the impact of such diets on the expression of miRNAs related to insulin regulation, revealing significant metabolic deterioration and brain inflammation.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 23, 2024·5 min read

Cycle of Decline: Neuron Aging in Alzheimer’s Unraveled

Neurons in Alzheimer’s disease patients tend to re-enter the cell cycle and quickly progress to senescence. Using advanced snRNA-seq techniques, researchers analyzed over 30,000 nuclei to track these changes, finding that these neurons often fail to complete the cell cycle and instead show signs of aging.

Featured Neurology Neuroscience

·April 22, 2024·6 min read

AI Links Gut Microbiome to Alzheimer’s

Researchers are pioneering the use of artificial intelligence to explore how the gut microbiome influences Alzheimer’s disease. Their latest study employs AI to analyze how metabolites produced by gut bacteria interact with cellular receptors, potentially contributing to Alzheimer's development.

Featured Genetics Neurology Neuroscience

·April 20, 2024·4 min read

New Insights into Protein Accumulation in Alzheimer’s

Researchers made a significant discovery in understanding the mechanisms behind protein accumulation in neurodegenerative diseases like Alzheimer’s. By studying fruit flies, the team found that a reduction in mitochondria within neuron axons leads directly to this detrimental protein buildup.

Featured Neurology Neuroscience

·April 16, 2024·5 min read

HIV Drugs May Reduce Alzheimer’s Risk

Common HIV drugs could reduce the incidence of Alzheimer’s disease (AD). Utilizing anonymized prescription data from over 225,000 individuals, the study found that HIV-positive patients taking reverse transcriptase (RT) inhibitors showed a significantly lower rate of AD compared to the general population.

Featured Neurology Neuroscience

·April 11, 2024·4 min read

Lucid Episodes in Dementia Explored

A new study explores lucid episodes in individuals with advanced dementia, revealing that these episodes are not confined to imminent death scenarios as previously thought. Surveying family caregivers, the researchers classified these episodes into types based on their quality and context, finding that 75% of those experiencing lucid moments had Alzheimer’s Disease.

Featured Genetics Neurology Neuroscience

·April 10, 2024·7 min read

Gene Variant Shields Against Alzheimer’s

Researchers identified a genetic variant that significantly lowers the risk of Alzheimer’s disease by up to 70%, potentially benefiting hundreds of thousands in the U.S. The variant, found in the fibronectin gene involved in the blood-brain barrier's function, aids in preventing amyloid accumulation in the brain, a hallmark of Alzheimer’s.

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Alzheimer’s disease

New Technique Reveals Rapid Aging in Alzheimer’s Brain Cells

Mini-Brains from Stem Cells Provide Hope for Alzheimer’s Diagnosis

tRNA Fragments Linked to Alzheimer’s

Youth-Onset Diabetes Linked to Higher Alzheimer’s Risk

APOE4 Gene Doubles Up Alzheimer’s Risk

High-Fat Diet Linked to Alzheimer’s Through Molecular Changes

Cycle of Decline: Neuron Aging in Alzheimer’s Unraveled

AI Links Gut Microbiome to Alzheimer’s

New Insights into Protein Accumulation in Alzheimer’s

HIV Drugs May Reduce Alzheimer’s Risk

Lucid Episodes in Dementia Explored

Gene Variant Shields Against Alzheimer’s

AI Found the Key to Pre-Symptom Alzheimer’s

43% of Antipsychotics for Seniors Start in Hospitals

One Protein Switches Roles to Build the Brain and Its Blood Vessels

How the Brain Transforms Daily Life into Surreal Dreams

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