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Alzheimer’s disease

This shows an older man and a brain scan.

·June 21, 2024·4 min read

Ozempic May Reduce Alzheimer’s Risk

GLP-1 agonists like Ozempic reduce the risk of dementia in type 2 diabetes patients. The research followed over 88,000 individuals for up to ten years, showing a 30% lower risk compared to sulfonylureas and a 23% lower risk compared to DPP-4 inhibitors. These findings can guide doctors in selecting medications for older diabetes patients. However, further randomized trials are needed to confirm these results.

Featured Neurology Neuroscience

·June 21, 2024·8 min read

Synthetic Peptide Reverses Alzheimer’s Symptoms

Researchers reversed Alzheimer's symptoms in mice using a synthetic peptide, PHDP5, that targets brain function. The study shows that PHDP5 can cross the blood-brain barrier and restore memory by improving synaptic function. The treatment could delay cognitive decline if administered early. This breakthrough paves the way for new Alzheimer's therapies focusing on brain structure and function.

Featured Genetics Neurology Neuroscience

·June 17, 2024·6 min read

Maternal Alzheimer’s: A Risk Factor for Brain Changes

A new study finds that inheriting Alzheimer's risk from your mother, regardless of her age at onset, is linked to increased amyloid levels in the brain. This protein is a hallmark of Alzheimer's disease. The findings suggest maternal history of memory impairment, even without a formal diagnosis, could be a crucial factor in identifying individuals at risk of Alzheimer's.

Featured Neurology Neuroscience

·June 10, 2024·2 min read

FDA Panel Backs Donanemab: New Hope for Early Alzheimer’s Treatment

Eli Lilly’s Alzheimer’s drug, Donanemab, has been recommended for FDA approval by an independent panel. The drug has shown promise in slowing early-stage Alzheimer’s, despite risks like brain swelling. This recommendation follows a prior FDA rejection due to insufficient data. If approved, Donanemab could revolutionize Alzheimer's treatment, offering new hope for patients and their families.

This shows blue pills in an old man's hand.

Featured Neurology Neuroscience

·June 8, 2024·4 min read

Viagra Shows Promise in Boosting Brain Blood Flow for Dementia Prevention

A new study reveals that sildenafil (Viagra) enhances brain blood flow and improves blood vessel function in patients at risk of vascular dementia. This study marks a significant advancement in addressing this condition. The team found that sildenafil increased blood flow in the brain's small and large vessels, potentially preventing dementia. These findings highlight the drug's promise for larger-scale trials to confirm its effectiveness.

Featured Neurology Neuroscience

·June 6, 2024·5 min read

MRI Method Predicts Dementia 9 Years in Advance with 80% Accuracy

Researchers developed a method to predict dementia with over 80% accuracy up to nine years before diagnosis. Using fMRI scans, the team analyzed changes in the brain's default mode network (DMN), which is affected early in Alzheimer's disease. This approach outperforms traditional memory tests and brain shrinkage measurements. The study used data from over 1,100 volunteers and highlights potential applications for early intervention.

Featured Neurology Neuroscience

·May 31, 2024·3 min read

Ketones May Help Reverse Cognitive Decline

As we age, our brain naturally becomes more insulin resistant, disrupting neuron communication and leading to cognitive decline and neurodegeneration. Researchers studied how acute insulin resistance impacts neuronal function before symptoms of chronic conditions like Alzheimer's manifest.

Featured Neurology Neuroscience

·May 29, 2024·6 min read

Early Memory Complaints Linked to Alzheimer’s Brain Changes

A new study finds that reports of cognitive decline from patients and their partners are linked to the accumulation of tau tangles, a hallmark of Alzheimer's disease. This underscores the importance of addressing memory concerns early.

Featured Neurology Neuroscience

·May 27, 2024·4 min read

New Alzheimer’s Breakthrough Targets Plexin-B1 Protein

Researchers identified a novel way to potentially slow or halt Alzheimer's progression by targeting the plexin-B1 protein. Their study shows how reactive astrocytes and plexin-B1 play crucial roles in clearing amyloid plaques. This discovery opens new pathways for Alzheimer's treatments and emphasizes the importance of cellular interactions.

Featured Neurology Neuroscience

·May 26, 2024·7 min read

Nostalgic Music Affects the Brain and Memory

Nostalgic music activates brain areas linked to memory, reward, and self-processing. This discovery could help improve the quality of life for those with dementia.

Featured Neurology Neuroscience

·May 22, 2024·4 min read

Pomegranate Power: Compound May Aid Memory in Alzheimer’s

A new study finds that urolithin A, a substance found in pomegranates, can improve memory and may help treat Alzheimer's disease. This natural compound works by removing damaged mitochondria from the brain, similar to the effects of NAD supplements. While dosage is still being determined, this discovery offers promising potential for treating and preventing neurodegenerative diseases.

Featured Neurology Neuroscience

·May 21, 2024·3 min read

Gut Bacteria’s Link to Alzheimer’s Explored

Researchers are investigating the connection between gut bacteria and Alzheimer's disease. They believe harmful metabolites from bad bacteria can travel to the brain, causing inflammation and potentially triggering dementia.

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Alzheimer’s disease

Ozempic May Reduce Alzheimer’s Risk

Synthetic Peptide Reverses Alzheimer’s Symptoms

Maternal Alzheimer’s: A Risk Factor for Brain Changes

FDA Panel Backs Donanemab: New Hope for Early Alzheimer’s Treatment

Viagra Shows Promise in Boosting Brain Blood Flow for Dementia Prevention

MRI Method Predicts Dementia 9 Years in Advance with 80% Accuracy

Ketones May Help Reverse Cognitive Decline

Early Memory Complaints Linked to Alzheimer’s Brain Changes

New Alzheimer’s Breakthrough Targets Plexin-B1 Protein

Nostalgic Music Affects the Brain and Memory

Pomegranate Power: Compound May Aid Memory in Alzheimer’s

Gut Bacteria’s Link to Alzheimer’s Explored

Compound BA-101 Reverses Glioblastoma Chemo Resistance

Myelin Damage Triggers Abnormal Brain Rhythms During Sleep

NFL Players Face Fourfold Increase in Neurodegenerative Mortality

Eye Movements Form a Unique Gaze Fingerprint

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