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Alzheimer’s disease

·March 31, 2025·5 min read

Less Deep Sleep Linked to Brain Shrinkage, Alzheimer’s Risk

New research shows that reduced time in slow wave and REM sleep is associated with smaller brain volumes in regions vulnerable to Alzheimer’s disease. Using sleep studies and brain imaging data from 270 participants, researchers found that poor sleep architecture was linked to brain atrophy over time—particularly in the inferior parietal region, an area affected early in Alzheimer’s.

Featured Neurology Neuroscience

·March 31, 2025·4 min read

Smell Test at Home May Sniff Out Early Cognitive Decline

A new study highlights that olfactory testing could offer a simple, cost-effective way to detect early cognitive impairment from home. Researchers found that older adults with mild cognitive issues performed worse on odor identification and memory tasks than cognitively normal individuals.

Featured Neurology Neuroscience

·March 27, 2025·5 min read

Type 2 Diabetes Rewires the Brain Like Early Alzheimer’s

New research reveals that Type 2 diabetes may impair the brain’s reward and memory processing in ways that mirror early Alzheimer’s disease. The study focuses on the anterior cingulate cortex (ACC), a brain region responsible for motivation and emotional regulation, and its interaction with the hippocampus.

Featured Neurology Neuroscience

·March 25, 2025·6 min read

ADHD May Raise Dementia Risk

A new study finds that adults with ADHD show brain changes similar to those seen in early-stage dementia, including higher iron accumulation and increased neurofilament light chain (NfL) levels in the blood. Using advanced MRI scans and blood tests, researchers identified elevated iron in key brain regions and signs of nerve damage in ADHD patients compared to healthy individuals.

Featured Neurology Neuroscience

·March 20, 2025·3 min read

Changes in Sleep Patterns Could Predict Dementia Risk

A new study finds that women in their 80s who develop increasing daytime sleepiness over five years are twice as likely to develop dementia. Researchers tracked 733 women without cognitive impairment, using wrist devices to monitor sleep and circadian rhythms.

This shows an older woman, a clock and fresh foods.

Featured Genetics Neurology Neuroscience

·March 14, 2025·5 min read

Turn Back Your Brain’s Bioenergetic Clock to Reduce Alzheimer’s Risk

Researchers have discovered that a person's "bioenergetic age," reflecting how efficiently cells produce energy, strongly predicts Alzheimer's risk and progression. High blood levels of molecules called acylcarnitines, markers of aging metabolism, were linked to faster cognitive decline and greater Alzheimer’s symptoms.

Featured Genetics Neurology Neuroscience

·March 6, 2025·4 min read

Mapping Brain Cells Vulnerable to Alzheimer’s Protein Buildup

Researchers have identified memory-related brain cells that are highly vulnerable to tau protein accumulation, a key factor in Alzheimer’s disease. Using the MISS brain-mapping technique, they profiled 1.3 million cells in mice to pinpoint which cell types are most affected.

Featured Genetics Neurology Neuroscience

·February 27, 2025·3 min read

Alzheimer’s Study Identifies 16 Risk Genes

A large whole-genome sequencing study has uncovered 16 new genes linked to Alzheimer’s disease, expanding genetic research beyond European ancestry. Researchers analyzed data from 49,149 individuals, nearly half of whom were from underrepresented populations, to improve understanding of genetic risk factors.

Featured Neurology Neuroscience

·February 15, 2025·5 min read

Brain Bleeds Double Dementia Risk

Researchers have found that intracranial hemorrhages, or "brain bleeds," double the risk of developing dementia later in life. While ischemic strokes caused by blood clots have long been linked to cognitive decline, this study shows that hemorrhages also significantly increase dementia risk. Using Medicare data from nearly 15,000 patients, scientists observed a two-fold increase in dementia diagnosis within about 5.6 years after a brain bleed.

Featured Neurology Neuroscience

·January 31, 2025·5 min read

Imaging Reveals Gut-Brain Connection in Alzheimer’s Disease

Scientists have used advanced X-ray phase-contrast tomography (XPCT) to uncover how gut health may influence Alzheimer’s disease. The study found structural changes in the gut of Alzheimer’s-affected mice, revealing abnormalities in intestinal cells, neurons, and mucus secretion.

Featured Neurology Neuroscience

·January 27, 2025·5 min read

REM Sleep Delays May Indicate Early Alzheimer’s

Delayed rapid eye movement (REM) sleep may be an early indicator of Alzheimer’s disease. Researchers found that participants with delayed REM sleep had higher levels of toxic proteins associated with Alzheimer’s and reduced levels of brain-derived neurotrophic factor (BDNF), which supports memory.

Featured Neurology Neuroscience

·January 21, 2025·6 min read

Antibiotics and Other Drugs May Reduce Dementia Risk

A study analyzing data from over 130 million individuals found that antibiotics, antivirals, vaccines, and anti-inflammatory medications are associated with a reduced risk of dementia. This supports the idea that infections and inflammation contribute to dementia and highlights the potential of repurposing existing drugs for prevention or treatment.