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Alzheimer’s disease

·May 21, 2025·4 min read

Cold Sore Virus Linked to Alzheimer’s, Antivirals May Lower Risk

A large study suggests that symptomatic infection with herpes simplex virus 1 (HSV-1)—best known for causing cold sores—may significantly raise the risk of developing Alzheimer’s disease. Researchers found that people with HSV-1 were 80% more likely to have Alzheimer’s, while those treated with antiviral medications had a 17% lower risk.

This shows an older man sitting and brains.

Featured Genetics Neurology Neuroscience

·May 18, 2025·4 min read

Sitting for Hours May Shrink the Brain

Prolonged sedentary behavior in adults over 50 is linked to cognitive decline and brain shrinkage in regions vulnerable to Alzheimer’s disease. Even among those who exercise regularly, spending more time sitting was associated with worse cognitive outcomes.

Featured Neurology Neuroscience Psychology

·May 17, 2025·5 min read

Midlife Cortisol Levels Linked to Alzheimer’s Risk

A new study finds that elevated cortisol levels in midlife are linked to increased brain amyloid deposition—a key marker of Alzheimer’s disease—specifically in post-menopausal women. Researchers tracked 305 cognitively healthy individuals over 15 years and discovered that high cortisol predicted amyloid buildup later in life, but only among women who had gone through menopause.

Featured Genetics Neurology Neuroscience

·May 17, 2025·5 min read

Alzheimer’s Disrupts the Whole Body, Not Just the Brain

Alzheimer’s disease is traditionally seen as a brain disorder, but new research using fruit flies reveals that it also affects organs and tissues throughout the body. Scientists created an Alzheimer’s Disease Fly Cell Atlas to profile gene expression across 219 cell types in flies expressing human Alzheimer’s proteins.

Featured Neurology Neuroscience

·May 8, 2025·4 min read

HIV Drugs Linked to Lower Alzheimer’s Risk

New research shows that HIV drugs called NRTIs may significantly reduce the risk of developing Alzheimer’s disease. Analyzing two large health databases, scientists found that patients on NRTIs had a 6% to 13% annual decrease in Alzheimer’s risk.

Featured Neurology Neuroscience Psychology

·May 7, 2025·4 min read

Knowing Alzheimer’s Risk Lowers Anxiety, But Motivation Fades

A new study shows that learning about amyloid beta buildup — a risk factor for Alzheimer’s disease — does not increase emotional distress, but motivation to maintain healthy habits declines over time. Healthy adults who learned they had no amyloid buildup reported reduced depression, anxiety, and memory concerns, yet also lost motivation to continue positive lifestyle changes.

Featured Neurology Neuroscience

·May 7, 2025·9 min read

Want to Know Your Alzheimer’s Risk? Many Change Their Minds

New research reveals a striking gap between people’s theoretical desire to know their Alzheimer’s disease risk and their real-life decisions when results are actually offered. In a study of cognitively normal volunteers, only 60% chose to learn their estimated risk when given the chance, despite 81% expressing prior interest.

Featured Neurology Neuroscience

·April 28, 2025·3 min read

Immune Dysfunction May Drive Alzheimer’s Progression

A new study highlights a potential role for immune system dysfunction in the onset and progression of Alzheimer's disease. Researchers found that neuroinflammation, trained innate immune memory, and cellular reprogramming may interact with amyloid and tau proteins to drive disease pathology.

Featured Genetics Neurology Neuroscience

·April 25, 2025·7 min read

AI Uncovers New Cause of Alzheimer’s

Researchers have discovered that a gene previously seen as a biomarker for Alzheimer’s disease, PHGDH, actually plays a causal role by disrupting gene regulation in the brain. Using AI, the team revealed that PHGDH has a hidden DNA-binding function unrelated to its known enzymatic activity. This malfunction triggers early Alzheimer’s development, offering a new target for prevention.

This shows an older lady exercising and a brain.

Featured Neurology Neuroscience

·April 25, 2025·9 min read

Low and Moderate Exercise May Help Prevent Alzheimer’s Decline

New findings from the EXERT study reveal that both low and moderate-high intensity exercise may help preserve cognitive function in older adults with mild memory problems, a major risk factor for Alzheimer’s disease. Over 12 months, participants who engaged in either form of exercise showed significantly less cognitive decline and reduced brain volume loss, especially in the prefrontal cortex, compared to a usual-care group.

Neuroscience

·April 25, 2025·5 min read

Blue Brain Marker Peaks in Midlife, May Predict Cognitive Aging

Researchers have mapped age-related changes in the brain’s locus coeruleus (LC), a region linked to cognition and Alzheimer’s risk, by tracking neuromelanin, a pigment that gives it its signature blue hue. In a diverse group of participants aged 19 to 86, they found an inverted U-shaped pattern: LC signal peaked in late middle age, then declined.

Featured Neurology Neuroscience

·April 24, 2025·3 min read

Metabolic Syndrome in Midlife Linked to Higher Dementia Risk

A large-scale study has found that having metabolic syndrome in midlife—marked by excess belly fat, high blood pressure, and abnormal cholesterol or blood sugar—is associated with a significantly higher risk of developing young-onset dementia before age 65. The analysis, based on nearly two million people, showed that the more components of metabolic syndrome a person had, the greater their dementia risk, with women and those in their 40s being most vulnerable.

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Alzheimer’s disease

Cold Sore Virus Linked to Alzheimer’s, Antivirals May Lower Risk

Sitting for Hours May Shrink the Brain

Midlife Cortisol Levels Linked to Alzheimer’s Risk

Alzheimer’s Disrupts the Whole Body, Not Just the Brain

HIV Drugs Linked to Lower Alzheimer’s Risk

Knowing Alzheimer’s Risk Lowers Anxiety, But Motivation Fades

Want to Know Your Alzheimer’s Risk? Many Change Their Minds

Immune Dysfunction May Drive Alzheimer’s Progression

AI Uncovers New Cause of Alzheimer’s

Low and Moderate Exercise May Help Prevent Alzheimer’s Decline

Blue Brain Marker Peaks in Midlife, May Predict Cognitive Aging

Metabolic Syndrome in Midlife Linked to Higher Dementia Risk

3D-Printed “Honeycomb” Sensors Match Your Unique Neural Map

Glutathione Prevents Cellular Clogs

Cortisol Kill-Switch: Exercise Rewires Stress Biology

AI Restores Voices Through Microscopic Neck Movements

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