FeaturedNeuroscience·June 28, 2022·5 min readNew Brain Mechanism Involved in Impulsive Cocaine-Seeking in Rats DiscoveredBlocking M2Rs muscarinic acetylcholine receptors in the lateral habenula with an experimental drug increased cocaine-seeking behaviors in rat models of impulsive behaviors.Read More
FeaturedNeuroscience·June 27, 2022·5 min readMolecular Mechanisms Behind Learning and Memory IdentifiedFindings reveal the molecular mechanism for acetylcholine in learning and memory.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·May 26, 2022·3 min readSynaptic Connectivity of a Novel Cell Population in the StriatumResearchers characterize a novel neural population within the striatum that appears to be responsible for the interplay between acetylcholine and GABA.Read More
FeaturedGeneticsNeurosciencePsychology·April 7, 2022·6 min readHuman Gene Variant Produces Attention Deficit Disorder-Like Problems in MiceMice with the Val89 choline transporter variant had reduced rates of choline uptake and a diminished capacity to sustain acetylcholine production during attention-demanding conditions. The effect led to decreased cognitive performance when the mice were faced with additional challenges.Read More
FeaturedNeuroscience·March 24, 2022·8 min readA Mechanism That Underlies Local Dopamine Release in the BrainAcetylcholine can trigger the firing of dopamine neurons by binding to parts of these neurons not previously known to initiate firing.Read More
AutismFeaturedNeurosciencePsychology·March 9, 2022·4 min readHow Early Life Experiences May Affect Brain WiringEarly life experiences may affect neural wiring patterns that can lead to the development of ASD, schizophrenia, and epilepsy later in life, a new study reports.Read More
ElectrophysiologyFeaturedNeuroscience·October 28, 2021·3 min readHow Nicotine Influences Hippocampal Dependent CognitionNicotine exposure significantly altered the metabolism and secretion of serotonin, acetylcholine, kynurenic acid, and choline in HT22 hippocampal cells. Findings suggest nicotine could have neuroprotective properties and provide cognitive enhancement.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·September 16, 2021·3 min readDrug Targets for Memory EnhancementResearchers identified specific receptors for acetylcholine that reroute information flow through memory circuits in the hippocampus. The findings could have implications for the development of drugs to help enhance or protect memory from diseases associated with cognitive decline.Read More
FeaturedNeurosciencePsychology·May 19, 2021·6 min readCommonly Used Drugs for Schizophrenia Linked to Greater Cognitive ImpairmentMedications with anticholinergic properties given to help reduce physical and mental health symptoms associated with schizophrenia have a cumulative effect in reducing cognitive function in patients.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·May 5, 2021·4 min readA Possible Novel Migraine TherapyFindings suggest developing HDAC6 inhibitors could be a novel new therapeutic avenue for the treatment of migraines.Read More
FeaturedNeurologyNeuroscience·March 27, 2021·4 min readCommon Alzheimer’s Treatment Linked to Slower Cognitive DeclineCholinesterase inhibitors such as galantamine, donepezil, and rivastigmine, appear to generate persistent cognitive benefits, and increased longevity for up to five years in Alzheimer's patients.Read More
FeaturedNeuroscience·February 10, 2021·4 min readHow the Brain Makes Sense of TouchStudy identifies specific neurons that help activate sensory processing in nearby nerve cells. The findings suggest ways the brain integrates signals essential for tactile perception and learning.Read More
