Summary: When a rat helps another within its social group, brain areas associated with reward and motivation become more active. This does not occur when a rat is faced with the prospect of helping another rat outside its social group. Researchers say the findings may provide a better understanding of similar social biases in humans.
Rescuing a member of their own social group, but not a stranger, triggers motivational and social reward centers in rats’ brains, suggests a report published today in eLife.
The study provides the first description of similar brain activity in both rats and humans underlying this socially biased behaviour. The findings add to our understanding of social biases and could help with developing ways to promote cooperation outside of an individual’s social group.
“Humans, as well as many other creatures, are biased toward helping other members of their social groups over individuals they view as outsiders, and this can have a negative impact in diverse societies where different groups need to cooperate in order to thrive,” says first author Inbal Ben-Ami Bartal, a faculty member at the Sagol School of Neuroscience and the Psychology Department at Tel-Aviv University, Israel.
“Understanding the brain mechanisms underlying these biases is essential to finding ways to eliminate them.”
To explore this further, Bartal and a multinational team of colleagues placed rats in a situation where either a cage mate of the same type of rat, or a different type of rat they had never met, was trapped. In the experiments, most rats learned to free their cage mate, but few rescued the stranger.
The team then examined the brain activity associated with these behaviours to understand why the rats were biased towards helping their cage mates. They found that some regions of the brain are activated in response to the distress of either a cage mate or an unfamiliar rat, meaning that rats sense the distress of another animal whether or not they know them. But additional brain regions associated with reward seeking and positive social experiences were turned on only when a cage mate was in distress.
“This brain activity in the rats that helped their fellow group members suggests an empathetic response to their distress,” Bartal says.
Previous studies in humans have also suggested that empathy towards fellow group members drives the desire to help them but not strangers. The current findings suggest that similar brain activity may drive these social biases in rats and potentially other mammals.
“We’ve provided the first evidence for a common biological mechanism driving empathic helping behaviours in humans and rats in response to the distress of friends,” concludes senior author Daniela Kaufer, Professor at the Department of Integrative Biology and the Helen Wills Neuroscience Institute at the University of California, Berkeley, US.
“Our results lay the groundwork for future studies to better understand the brain activity involved and why it causes us to choose helping some people over others.”
About this social neuroscience research news
Source: eLife Contact: Emily Packer – eLife Image: The image is credited to Inbal Ben-Ami Bartal
Neural correlates of ingroup bias for prosociality in rats
Prosocial behavior, in particular helping others in need, occurs preferentially in response to distress of one’s own group members. In order to explore the neural mechanisms promoting mammalian helping behavior, a discovery-based approach was used here to identify brain-wide activity correlated with helping behavior in rats.
Demonstrating social selectivity, rats helped others of their strain (‘ingroup’), but not rats of an unfamiliar strain (‘outgroup’), by releasing them from a restrainer. Analysis of brain-wide neural activity via quantification of the early-immediate gene c-Fos identified a shared network, including frontal and insular cortices, that was active in the helping test irrespective of group membership.
In contrast, the striatum was selectively active for ingroup members, and activity in the nucleus accumbens, a central network hub, correlated with helping. In vivo calcium imaging showed accumbens activity when rats approached a trapped ingroup member, and retrograde tracing identified a subpopulation of accumbens-projecting cells that was correlated with helping.
These findings demonstrate that motivation and reward networks are associated with helping an ingroup member and provide the first description of neural correlates of ingroup bias in rodents.