Digestive Diseases Linked to Loneliness and Depression in Older Adults

Summary: Rising life expectancy is accompanied by a surge in digestive diseases, affecting 40% of US adults. Researchers discovered a correlation between digestive diseases and rates of loneliness, depression, and social isolation among older adults.

Their study, leveraging data from the University of Michigan Health and Retirement Study, highlights the often-overlooked psychosocial factors impacting gastrointestinal health. The study emphasizes the importance of screening for mental health factors alongside physical symptoms to provide holistic patient care.

Key Facts:

  1. Nearly 40% of US adults report living with some form of digestive disease.
  2. Research showed a notable connection between loneliness, depression, and the prevalence of digestive diseases.
  3. Out of 7,110 participants, 60.4% with digestive diseases reported loneliness, compared to 55.6% without such diseases.

Source: University of Michigan

While life expectancy rates for older Americans are rising, nearly 40% of adults report living with a digestive disease of some kind.

“Many people don’t realize that these conditions are very common in ambulatory care,” said Michigan Medicine gastroenterologist Shirley Ann Cohen-Mekelburg, M.D., who specializes in conditions like inflammatory bowel disease, Crohn’s disease and ulcerative colitis.

“Ultimately, this creates an excess in health care spending in the United States. Not only are these conditions debilitating for the millions of people living with them, but they’re also very expensive to treat.”

This shows a lonely older man.
Out of a pool of 7,110 participants, the team identified 56% of individuals with a digestive disease and 44% without one. Credit: Neuroscience News

Cohen-Mekelburg says that in recent years, there has been a greater emphasis among providers in detecting why so many Americans are developing digestive diseases.

However, she notes that current approaches often fail to consider how things like psychosocial factors contribute to these conditions. 

“As physicians, it’s important for us to pay attention to psychosocial factors involved in the lives of our patients, but they often go overlooked,” she said.

“These factors have the potential to significantly impact gastrointestinal health, and they also play a crucial role in the overall wellbeing of our patients.”

This notion inspired Cohen-Mekelburg and a team of fellow gastroenterologists and hepatologists to examine the rates of loneliness, depression and social isolation in older adults both with and without digestive diseases.

Their findings were recently published in Clinical Gastroenterology and Hepatology.

Cohen-Mekelburg notes that the team also “wanted to quantify these numbers with self-reported rates of poor health.”

“Our research involved analyzing data from 2008 to 2016 from the University of Michigan Health and Retirement Study.

This is a longitudinal panel study that involves a representative sample of approximately 20,000 individuals in the U.S. who are 50 years and older, as well as their spouses,” she said.

“It’s important to note that loneliness refers to the subjective distressed feeling of being alone or lacking companionship. The correlation between loneliness and depression is well established.”

However, Cohen-Mekelburg adds that social isolation refers to the “objective physical separation from other people, which is independent of psychological well-being.”

“Therefore, there are people who live in isolation but are well-adapted, not lonely and report high psychological wellbeing. But on the other hand, there are also people who are socially connected, yet suffer from low psychological wellbeing and loneliness. This, despite having a strong social network.”

Out of a pool of 7,110 participants, the team identified 56% of individuals with a digestive disease and 44% without one.

“Overall, 60.4% and 55.6% of respondents with and without digestive diseases reported loneliness, while 12.7% and 7.5% reported severe depression, and 8.9% and 8.7% reported social isolation, respectively,” said Cohen-Mekelburg.

“We found that individuals with a digestive disease were more likely to report ‘poor-or-fair’ health when compared to those without one. And among patients with a digestive disease, loneliness, as well as moderate to severe depression, were associated with greater odds of self-reporting ‘poor-or-fair’ health.”

Cohen-Mekelburg says that she hopes these findings eventually empower gastroenterologists to “screen patients for depression and loneliness,” in addition to their physical symptoms. “By doing this, providers can better establish care pathways for mental health treatment for their patients, which is hugely important,” she said.

“Our research shows that gastroenterologists are in a unique position to help their patients achieve good overall health. If you’re a clinician who also happens to treat older adults, even better. Being aware of the link between loneliness, depressive symptoms and digestive diseases can really benefit your patients from a holistic perspective.”

About this aging, digestion, and depression research news

Author: Patricia DeLacey
Source: University of Michigan
Contact: Patricia DeLacey – University of Michigan
Image: The image is credited to Neuroscience News

Original Research: Closed access.
Loneliness and Depressive Symptoms are High Among Older Adults with Digestive Disease and associated with Lower Perceived Health” by Shirley Ann Cohen-Mekelburg et al. Clinical Gastroenterology and Hepatology


Abstract

Loneliness and Depressive Symptoms are High Among Older Adults with Digestive Disease and associated with Lower Perceived Health

Background and Aims

Current approaches to managing digestive disease in older adults fail to consider the psychosocial factors contributing to a person’s health. We aimed to compare the frequency of loneliness, depression, and social isolation in older adults with and without a digestive disease and to quantify their association with poor health.

Methods

We conducted an analysis of Health and Retirement Study data from 2008-2016, a nationally representative panel study of participants 50 years and older and their spouses. Bivariate analyses examined differences in loneliness, depression, and social isolation among patients with and without digestive disease. We also examined the relationship between these factors and health.

Results

We identified 3,979(56.0%) respondents with and 3,131(44.0%) without a digestive disease. Overall, 60.4% and 55.6% of respondents with and without digestive disease reported loneliness(p<0.001), 12.7% and 7.5% reported severe depression(p<0.001), 8.9% and 8.7% reported social isolation(p=NS), respectively. After adjusting for covariates, those with a digestive disease were more likely to report poor-or-fair health than those without digestive disease (OR 1.25,95%CI 1.11,1.41). Among patients with a digestive disease, loneliness (OR 1.43,95%CI 1.22,1.69) and moderate and severe depression (OR 2.93,95%CI 2.48,3.47; OR 8.96,95%CI 6.91,11.63) were associated with greater odds of poor-or-fair health.

Conclusion

Older adults with a digestive disease were more likely than those without a digestive disease to endorse loneliness and moderate-to-severe depression and these conditions are associated with poor-or-fair health. Gastroenterologists should feel empowered to screen patients for depression and loneliness symptoms and establish care pathways for mental health treatment.

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