Researchers have discovered a potential drug which can force BACE into different parts of a cell, reducing its ability to produce amyloid beta.
Researchers transform iPSCs into neurons to test the efficacy of drugs to treat Alzheimer’s disease.
Mutations in the alpha-synuclein gene can cause increased vulnerability to pesticides, which may lead to Parkinson’s disease.
Infants who carry a gene associated with an increased rick for Alzheimer’s disease have differences in brain development compared to those who do not carry the gene, a new study reports.
Researchers discover the expression of certain clock genes plays a critical role in delaying the emergence of age-related signs in the brain.
Microglia plays crucial roles both in healthy and diseased brains, a new study reports.
Researchers use RNAi to reveal dozens of genes which could represent new therapeutic targets for treating Parkinson’s disease.
A new study reports even low levels of APOE4 can increase beta-amyloid plaques in the brain and neuronal damage in mouse models of Alzheimer’s disease. However, introducing APOE2 can reduce amyloid deposits and other associated damage.
According to a comprehensive systematic review, available evidence does not support an association between statins and cognitive decline.
Researchers use a novel sequencing method to identify a group of genes used by microglia to sense pathogenic organisms, toxins and damaged neurons.