A new brain tissue study has shown gene expression in bipolar patients treated with antipsychotic medications is similar to the expression in subjects with no history of bipolar disorder.
Adapting two dimensional culture methods to grow 3-D neuron structures from induced pluripotent stem cells, researchers may be able to model and study neurodegenerative disorders such as Alzheimer’s disease.
‘HD in a dish’ will facilitate search for elusive treatment. An international consortium of Huntington’s disease experts, including several from the Sue and Bill Gross Stem Cell Research Center at UC Irvine, has generated a human model of the deadly inherited disorder directly from the skin cells of affected patients. The re-created neurons, which live [...]
Innovative technique lays groundwork for novel stem cell therapies Scientists at the Gladstone Institutes have for the first time transformed skin cells—with a single genetic factor—into cells that develop on their own into an interconnected, functional network of brain cells. The research offers new hope in the fight against many neurological conditions because scientists expect [...]
Researchers from the University of Minnesota’s Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that – for the first time – makes the production of human muscle cells from stem cells efficient and effective. The research, published today in Cell Stem Cell, outlines the strategy [...]
Until recently, the production of pluripotent “multipurpose” stem cells from skin cells was considered to be the ultimate new development. In the meantime, it has become possible to directly convert cells of the body into one another – without the time-consuming detour via a pluripotent intermediate stage. However, this method has so far been rather [...]