Researchers discover evidence of altered circadian rhythms and disrupted brain gene orchestration in patients with major depression.
Discovery of key link between circadian rhythms and metabolism may lead to new therapies for sleep disorders and diabetes. The discovery of a major gear in the biological clock that tells the body when to sleep and metabolize food may lead to new drugs to treat sleep problems and metabolic disorders, including diabetes. Scientists at [...]
The molecular pathway that carries time-of-day signals from the body’s internal clock to ultimately guide daily behavior is like a black box, says Amita Sehgal, PhD, the John Herr Musser Professor of Neuroscience and Co-Director, Comprehensive Neuroscience Center, at the Perelman School of Medicine, University of Pennsylvania. Now, new research from the Sehgal lab is [...]
New research at Oregon State University provides evidence for the first time that disruption of circadian rhythms – the biological “clocks” found in many animals – can clearly cause accelerated neurodegeneration, loss of motor function and premature death. The study was published in Neurobiology of Disease and done by researchers at OSU and Oregon Health [...]