Postpartum Depression May Persist Three Years After Giving Birth

Summary: Study reveals one in four women experience symptoms of depression up to three years after giving birth. The risks are greater for women with a history of mood disorders and gestational diabetes.

Source: NIH

A National Institutes of Health study of 5,000 women has found that approximately 1 in 4 experienced high levels of depressive symptoms at some point in the three years after giving birth. The rest of the women experienced low levels of depression throughout the three-year span. The study was conducted by researchers at NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It appears in the journal Pediatrics.

The American Academy of Pediatrics recommends that pediatricians screen mothers for postpartum depression at well-child visits at one, two, four and six months after childbirth. Researchers identified four trajectories of postpartum depressive symptoms and the factors that may increase a woman’s risk for elevated symptoms. The findings suggest that extending screening for postpartum depressive symptoms for at least two years after childbirth may be beneficial, the authors write.

“Our study indicates that six months may not be long enough to gauge depressive symptoms,” said Diane Putnick, Ph.D., the primary author and a staff scientist in the NICHD Epidemiology Branch. “These long-term data are key to improving our understanding of mom’s mental health, which we know is critical to her child’s well-being and development.”

The researchers analyzed data from the Upstate KIDS study, which included babies born between 2008 and 2010 from 57 counties in New York State. The study followed 5,000 women for three years after their children were born.

This shows a mom walking with two kids
Women with underlying conditions, such as mood disorders and/or gestational diabetes, were more likely to have higher levels of depressive symptoms that persisted throughout the study period. Image is in the public domain

Researchers assessed women’s symptoms through a brief, five-item depression screening questionnaire, but the study did not clinically diagnose depression in the women. Women with underlying conditions, such as mood disorders and/or gestational diabetes, were more likely to have higher levels of depressive symptoms that persisted throughout the study period.

The researchers noted that the study participants were primarily white, non-Hispanic women. Future studies should include a more diverse, broad population to provide more inclusive data on postpartum depression, Dr. Putnick said.

About this postpartum depression research news

Source: NIH
Contact: Meredith Daly – NIH
Image: The image is in the public domain

Original Research: Closed access.
Trajectories of Postpartum Depressive Symptoms” by Diane L. Putnick, Rajeshwari Sundaram, Erin M. Bell, Akhgar Ghassabian, Risë B. Goldstein, Sonia L. Robinson, Yassaman Vafai, Stephen E. Gilman, Edwina Yeung. Pediatrics


Trajectories of Postpartum Depressive Symptoms

OBJECTIVES: To identify homogenous depressive symptom trajectories over the postpartum period and the demographic and perinatal factors linked to different trajectories.

METHODS: Mothers (N = 4866) were recruited for Upstate KIDS, a population-based birth cohort study, and provided assessments of depressive symptoms at 4, 12, 24, and 36 months postpartum. Maternal demographic and perinatal conditions were obtained from vital records and/or maternal report.

RESULTS: Four depression trajectories were identified: low-stable (74.7%), characterized by low symptoms at all waves; low-increasing (8.2%), characterized by initially low but increasing symptoms; medium-decreasing (12.6%), characterized by initially moderate but remitting symptoms; and high-persistent (4.5%), characterized by high symptoms at all waves. Compared with the high-persistent group, older mothers (maximum odds ratio [OR] of the 3 comparisons: 1.10; 95% confidence interval [CI]: 1.05 to 1.15) or those with college education (maximum OR: 2.52; 95% CI: 1.36 to 4.68) were more likely to be in all other symptom groups, and mothers who had a history of mood disorder (minimum OR: 0.07; 95% CI: 0.04 to 0.10) or gestational diabetes mellitus diagnosis (minimum OR: 0.23; 95% CI: 0.08 to 0.68) were less likely to be in other symptom groups. Infertility treatment, multiple births, prepregnancy BMI, gestational hypertension, and infant sex were not differentially associated with depressive symptom trajectories.

CONCLUSIONS: One-quarter of mothers in a population-based birth cohort had elevated depressive symptoms in 3 years postpartum. Screening for maternal depression beyond the postpartum period may be warranted, particularly after mood and diabetic disorders.

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