FeaturedGeneticsNeurologyNeurosciencePain·April 23, 2025·4 min readClearing Zombie Cells Eases Back PainA new preclinical study has found that two drugs—o-Vanillin and RG-7112—can clear “zombie cells” from spinal discs, potentially treating the root cause of chronic low back pain. These senescent cells accumulate with age or injury and cause inflammation, pain, and tissue damage.Read More
FeaturedNeuroscience·October 22, 2024·3 min read“Zombie” Aging Cells May Speed Up Brain DeclineRecent research shows that senescent, or "zombie," skin cells may accelerate aging throughout the body. When transplanted into a preclinical model, these cells caused senescence to spread to other organs, impairing muscle function and brain health.Read More
FeaturedGeneticsNeuroscience·October 16, 2022·5 min readScientists Reappraise the Role of ‘Zombie’ Cells That Anti-aging Medicine Has Sought to EliminateSome senescent (zombie) cells are embedded in young, healthy tissue and promote normal repair from damage, researchers say.Read More
FeaturedGeneticsNeuroscience·July 1, 2022·5 min readResearchers Uncover New Pathway for Accumulation of Age-Promoting ‘Zombie Cells’Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·March 23, 2021·5 min read‘Zombie’ Genes? Some Genes Come to Life in the Brain After DeathIn the hours after death, some cells in the human brain not only remain active, they grow in size.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology·January 3, 2019·4 min readObese Mice Lose Anxiety When ‘Zombie Cells’ Exit the BrainAccording to researchers, obese mice have increased levels of senescent cells in their brains, and these cells contribute to anxiety. Using senolytics to clear the cells helps to reduce anxiety related behaviors.Read More
FeaturedNeurologyNeuroscience·September 19, 2018·4 min readZombie Cells Found in Mouse Brains Prior To Cognitive LossResearchers report senescent, or Zombie, cells accumulate in certain neurons prior to cognitive loss. By preventing accumulation of these cells, researchers were able to diminish apoptosis, memory loss and tau aggregation.Read More
