In women, parts of the default mode network responsible for memory retrieval and recollection, and spatial cognition were more likely to be connected to the overall DMN network. The patterns of connectivity correlated with brain structures associated with short-term memory problems resembled alterations seen in preclinical Alzheimer's disease.
Using induced pluripotent stem cells derived from skin cells of people with Tourette syndrome, researchers create 3D brain organoid models of the basal ganglia, an area of the brain previously implicated in TS. The model reveals potential pathologies behind the disorder and could help fashion new therapies to treat TS.
While neuroimaging holds great potential in helping researchers link specific patterns of brain activity to mental health disorders, a new study finds there is still a way to go to effectively link neuroimaging results to specific mental health disorders.
During absence seizures, most neurons showed decreased activity. This, researchers say, explains the decrease in brain function and impaired consciousness during an absence epilepsy seizure.
Researchers have identified neural biomarkers associated with food and drug cravings. The findings could help pave the way for new treatments for addiction.
The common antidepressant Prozac (fluoxetine) provokes an inflammatory response in the amniotic sac. The findings may reveal the underlying factor of why women who take SSRI antidepressants are at higher risk of preterm birth.
The formation of plaques can cause the accumulation of spheroid-shaped swellings along axons near the amyloid plaque deposits. The swellings are caused by lysosomes, which digest cellular waste. As the swelling enlarges, it can block the transmission of signals from one area of the brain to another.