Study identifies the TLR7 gene as an essential player in the immune response against coronavirus infection.
NKAP-related syndrome, a newly identified neurodevelopmental disorder caused by mutations in the NKPA gene, causes developmental delays, intellectual disabilities, behavioral abnormalities, and musculoskeletal problems in children.
Kdm6a, a gene on the X chromosome appears to be associated with the development of autoimmune diseases, such as Multiple Sclerosis. The gene is expressed more in the immune cells of females than males. When Kdm6a was deleted in mouse models of MS, the animals had improved symptoms and reduced inflammation. The findings shed light on why women are more prone to autoimmune diseases than males.
Disruptions in maintaining X chromosome inactivation of T cells may explain why women are more prone to developing SLE than males.
Researchers have identified a specific mechanism involved in how females inherit traits. The findings could help reduce susceptibility to Fragile X and Rett syndrome, the researchers report.
Researchers report there may be a molecular placental pathway that allows females to be more resilient to maternal stress.
According to researchers, a drug approved by the FDA may reverse some of the symptoms associated with Fragile X syndrome. The drug can reverse hyper-excitability that leads to sensory hypersensitivity.
Mass General researchers have developed a strategy for treating disorders related to the X chromosome.
Despite growing evidence linking genetics to some criminal behavior, researchers report using genetic evidence is a court room is likely not to be an effective tool in persuading juries that a defendant is less culpable for their actions.
Researchers report a lack of a nutrient required for normal brain development may trigger a mild form of autism. The findings, published in BioEssays, suggests supplementing the diet with carnitine could prevent up to 20% of autism cases.
According to researchers, people with Fragile X have 'noisier' brains, which can impair information flow and make social interactions more difficult.
Researchers discover the genetic cause of an intellectual disability in four male patients in record time.
