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Wellcome Trust Sanger Institute

·November 20, 2024·6 min read

Human Cell Atlas Transforms Understanding of Disease

The Human Cell Atlas (HCA) consortium has published over 40 studies revealing groundbreaking insights into human biology through large-scale mapping of cells. These studies cover diverse areas such as brain development, gut inflammation, and COVID-19 lung responses, while also showcasing the power of AI in understanding cellular mechanisms.

Featured Genetics Neuroscience

·April 13, 2022·6 min read

Mutations Across Animal Kingdom Shed New Light on Aging

The longer the lifespan of a species, the slower the rate of mutations occur. The findings support the long-standing theory that somatic mutations play a role in aging.

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Brain Cancer Featured Neurology

·February 5, 2021·3 min read

New Drug Targets for Childhood Cancer Neuroblastoma Identified

Researchers discovered all neuroblastomas arise from a single type of embryonic cell called sympathoblasts. The findings could lead to new avenues of treatment for the aggressive childhood cancer.

Featured Neuroscience

·April 23, 2020·5 min read

Key nose cells identified as likely COVID-19 virus entry points

The receptor protein ACE2 and the TMPRSS2 protease that can activate SARS-CoV-2 entry are expressed in cells on the inner lining of the nose. Mucus producing goblet cells and ciliated cells in the nose have the highest levels of both proteins, making them the most likely initial infection route for coronavirus. Additional key entry points were found in the cells of the eye's cornea and the intestines. This suggests other points of infection could be via the tear ducts and through fecal-oral transmission.

Featured Neuroscience

·March 16, 2020·4 min read

New research on brain structure highlights cells linked to Alzheimer’s and autism

Astrocytes are not uniform, as previously believed, but take distinct molecular forms depending on their location in the cerebral cortex. Astrocytes also organize in layers in similar ways to neurons.