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virology

·March 23, 2020·3 min read

Tuberculosis BCG-based vaccine may be effective against COVID-19

VPM1002, a vaccine candidate based on the tuberculosis BCG vaccine, may be effective in protecting against COVID-19. Previous studies in mice have shown the BCG vaccine is effective at protecting against several respiratory viral infections. If effective against coronavirus, researchers hope the vaccine can bridge the time gap until a specific SARS-CoV-2 vaccine is available.

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·March 13, 2020·1 min read

Research team has isolated the COVID-19 virus

A team of Canadian researchers has isolated SARS-CoV-2, the viral agent responsible for COVID-19. Isolating the virus will help researchers worldwide to develop better diagnostic tests, treatments, and vaccines for the pandemic virus. It will also help researchers to better understand the virus biology, evolution, and viral shedding.

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·March 12, 2020·6 min read

Study details first known person-to-person transmission of new coronavirus in the USA

A new Lancet study describes the first locally-transmitted case of SARS-CoV-2, which causes COVID-19, in the USA from a woman who recently traveled to China and transmitted the infection to her husband.

This shows a woman and child in surgical masks

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·March 10, 2020·4 min read

Knowing more about a virus threat may not satisfy you

People who rate themselves as highly knowledgeable about new viral infection threats could also be more likely to believe they don't know enough.

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·March 9, 2020·5 min read

5.1 days incubation period for COVID-19

Researchers report the median time from exposure to symptoms for the COVID-19 virus is 5.1 days. 97.5% of people who develop symptoms of coronavirus will do so within 11.5 days of exposure. For every 10,000 people quarantined for 14 days, an estimated 101 would develop symptoms after release.

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·March 6, 2020·3 min read

Potential drug to block coronavirus identified

A clinically proven drug known to block an enzyme essential for the viral entry of Coronavirus into the lungs blocks the COVID 19 (SARS-CoV-2) infection. The drug, Camostat mesilate, is a drug approved in Japan to treat pancreatic inflammation. Results suggest this drug may also protect against COVID 19. Researchers call for further clinical trials.

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·February 29, 2020·5 min read

How to Prepare for a Coronavirus Outbreak in the U.S.

Researchers explain how the general public can help protect themselves and those around them from coronavirus.

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·February 29, 2020·9 min read

A big coronavirus mystery: What about the children?

Infectious disease experts report between 40% and 70% of adults could become infected with coronavirus during the outbreak. In a new interview, Dr. Lipsitch, head of Harvard's T.H. Chan School of Public Health's Center for Communicable Disease Dynamics, discusses the risks and spread potential of COVID-19, and addresses how the infection could impact children's' health.

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·October 21, 2019·8 min read

Polio-like disease AFM linked to enterovirus

Researchers detected immunological remnants of enterovirus in the nervous systems of more than 12 patients with acute flaccid myelitis (AFM). The findings provide the strongest evidence to date that AFM is caused by a virus. The discovery could lead to improved diagnostics for the condition and the development of a vaccine for AFM.

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·July 16, 2019·3 min read

Gut microbes protect against neurologic damage from viral infections

A healthy and diverse microbiome is essential for quickly clearing viral infections in the nervous system to prevent risks associated with multiple sclerosis. Mice with lower gut bacteria had weaker immune responses and were unable to eliminate viruses, leading to worsening paralysis. Those treated with antibiotics before infection had fewer microglia.

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·July 11, 2019·4 min read

Are the ‘viral’ agents of MS, ALS and schizophrenia buried in our genome?

Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia.

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·May 27, 2019·4 min read

Coat of proteins makes viruses more infectious and links them to Alzheimer’s disease

Herpes simplex virus type 1 (HSV-1) and respiratory syncytial virus (RSV) interact with biological fluids, creating a coat of proteins around the viral surface. This results in the viruses becoming more infectious and can contribute to the formation of amyloid plaques. In animal models, researchers found these viruses can bind to amyloid proteins, which aggregate into plaques that contribute to Alzheimer's disease. HSV-1 is able to accelerate the transformation of soluble amyloid proteins into amyloid plaques.

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