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University of Kentucky

This shows a doctor looking at a spinal cord x ray

·February 26, 2021·5 min read

The Impact of Patient Sex on Treatment Strategies for Spinal Cord Injuries

Both the ApoE genotype and the sex of the mouse impacted the manner in which the animals with spinal cord injury responded to hypoxia treatment. Females with the ApoE e4 gene had a negative response to intermittent hypoxia.

This shows the outline of a brain and head

Electrophysiology Featured Articles Neurology Neuroscience

·February 5, 2021·5 min read

A New Method to Predict Individual Risk of Cognitive Decline

Specific patterns of frontal brainwaves during everyday memory tasks help researchers to predict a patient's risk for developing mild cognitive impairment within five years.

Featured Neurology Open Neuroscience Articles

·August 24, 2020·5 min read

Insights Into New Form of Dementia

Study reveals new criteria that could differentiate between FTD and LATE.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 9, 2020·3 min read

First in-human study of drug targeting brain inflammation supports further development

MW189, a small molecule drug candidate, blocks abnormal inflammation in the brain which contributes to injury and disease induced neurological impairments.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 10, 2020·2 min read

Antibiotics could be promising treatment for form of dementia

Gentamicin and G418, two aminoglycoside antibiotics, were effective at correcting genetic mutations associated with a specific form of frontotemporal dementia. The findings are promising for the treatment of frontotemporal dementia.

Featured Neurology Neuroscience

·January 8, 2020·4 min read

Gut microbes may improve stroke recovery

Microbiota-derived short-chain fatty acids (SCFA) modulate stroke recovery. The effect was mediated by circulating lymphocytes on microglia activation. The study reports SCFAs could be a potential therapeutic to improve post-stroke recovery.

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Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 30, 2019·5 min read

When is Alzheimer’s not Alzheimer’s? Researchers characterize a different form of dementia

LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone.

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Featured Neurology

·April 2, 2019·2 min read

A “Low Dose Aspirin” for Dementia? Drug Ready for First in-Human Testing

MW-151, a new drug that blocks 'bad' inflammation in the brain is about to be tested in a new human trial. Researchers believe the new drug could help stave off dementia.

Featured Neuroscience Open Neuroscience Articles Psychology

·October 3, 2018·5 min read

Connection Between Cognitive Function and Diet

A new study reports the Ketogenic diet can help to improve cognition. The study reports the Ketogenic diet can help improve balance in the gut microbiome, lower blood glucose levels and increase the processes that help to clear amyloid beta from the brain.