Researchers used optogenetics techniques to stimulate specific brain areas to increase neurogenesis and the production of neural stem cells to improve memory, cognition, and emotional processing in animal models.
Researchers found significant differences in B cells in women with postpartum depression. B cells are important components of the immune system that help produce antibodies and secrete both pro and anti-inflammatory factors.
miRNA29 is a key cellular switch in controlling late-stage brain development. Deleting miRNA29 in mice resulted in problems associated with a range of neurodevelopmental problems, including autism and epilepsy.
Focusing attention on a neural pathway starting at the periaqueductal grey region of the midbrain, researchers made a novel discovery about how dopamine generates different pain responses in male and female mice. Findings indicate dopamine may reduce pain sensitivity in males, whereas, in females, dopamine helps focus attention elsewhere in the presence of pain.
MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.
Genes found in the placenta can accurately help predict the size of a baby's brain and its cognitive development, which, depending on other factors, could predict risk factors for schizophrenia in later life.
A new study reveals a novel genetic risk loci for Alzheimer's disease. Using single cell gene expression patterns, researchers found genetic changes are expressed in microglia cells. The mutations are associated with an increased risk of Alzheimer's disease.
Researchers report the formation of larger, more visible SOD1 aggregates may help to protect brain cells.
UNC researchers have identified a brain circuit that runs from near the front of the brain to the hippocampus that helps to control neurogenesis.
Damaging shock waves intensify deep within the brain following head impact, researchers report.