miRNA29 is a key cellular switch in controlling late-stage brain development. Deleting miRNA29 in mice resulted in problems associated with a range of neurodevelopmental problems, including autism and epilepsy. Read More
Focusing attention on a neural pathway starting at the periaqueductal grey region of the midbrain, researchers made a novel discovery about how dopamine generates different pain responses in male and female mice. Findings indicate dopamine may reduce pain sensitivity in males, whereas, in females, dopamine helps focus attention elsewhere in the presence of pain. Read More
MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain. Read More
Genes found in the placenta can accurately help predict the size of a baby's brain and its cognitive development, which, depending on other factors, could predict risk factors for schizophrenia in later life. Read More
Rare structural genetic variants could play a role in the development of schizophrenia. Read More
Virtual reality test could help reduce falls and related injuries in people with multiple sclerosis. Read More
A new study reveals a novel genetic risk loci for Alzheimer's disease. Using single cell gene expression patterns, researchers found genetic changes are expressed in microglia cells. The mutations are associated with an increased risk of Alzheimer's disease. Read More
Researchers report the formation of larger, more visible SOD1 aggregates may help to protect brain cells. Read More
UNC researchers have identified a brain circuit that runs from near the front of the brain to the hippocampus that helps to control neurogenesis. Read More
Damaging shock waves intensify deep within the brain following head impact, researchers report. Read More
A new study reveals molecular details of what happens when axons are damaged or completely severed. Read More
Researchers reveal the deletion of a specific protein in progenitor cells leads to disrupted brain development. Read More
