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tricyclic antidepressants

Featured Neuroscience Pain

·May 2, 2022·3 min read

How Antidepressants Treat Nerve Pain

Researchers identify the mechanisms behind tricyclic antidepressants' ability to help relieve nerve pain.

Featured Neuroscience Open Neuroscience Articles Psychology

·March 20, 2020·3 min read

New drug can ease the side effects of medication against severe depression

A new substance named Lu AF60097 may help reduce side effects from tricyclic antidepressants in those with severe depression.

Featured Neurology Neuroscience Psychology

·July 25, 2018·3 min read

Depression and Antidepressants Linked to Increased Risk of VTE

Researchers have identified a link between depression, antidepressant use and an increased risk of developing venous thromboembolism.

Featured Open Neuroscience Articles Psychology

·June 14, 2018·4 min read

Treatment Options For Nightmare Disorder in Adults

Researchers propose a variety of therapeutic approaches and medications to help combat adult nightmare disorder.

Featured Neurology

·September 5, 2017·4 min read

Longtime Antidepressant Could Slow Parkinson’s Progression

According to researchers, an antidepressant that has been available for more than 50 years could help slow the progression of Parkinson's disease. The drug, nortiptyline, has been shown to stop the growth of alpha synuclein.

Image shows a diagram explaining how amitriptyline allows drugs to pass the bbb.

Featured Neurology Neuroscience

·April 27, 2017·4 min read

Antidepressants May Enhance Drug Delivery to Brain

A new study reports an antidepressant temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain. The findings could have implications for treating neurological diseases from ALS to epilepsy.

Nine petri dishes with crystal violet staining for live cells.

Brain Cancer Featured

·September 24, 2015·3 min read

Blood Thinners and Antidepressants Cause Autophagy in Mouse Models of Brain Cancer

According to researchers, combining tricyclic antidepressants with blood thinners increased tumor autophagy in mouse models of glioblastoma brain cancer.