Reducing H3Q5dop in rat models of cocaine withdrawal significantly reversed cocaine mediated gene expression changes and reduced cocaine-seeking behaviors.
Serotonin can chemically attach to histone proteins in the cell nucleus to help regulate gene expression. The findings may provide a better understanding of an array of psychological disorders and neurodegenerative diseases.
Researchers discover elevated levels of TG2 in the prefrontal cortex of people who committed suicide.
