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thalamic reticular nucleus

this shows a brain drawn as a blue print

Featured Neurology Neuroscience Open Neuroscience Articles

·November 6, 2021·6 min read

Restoring Normal Sleep Reduces Amyloid-Beta Accumulation in Mouse Model of Alzheimer’s Disease

Restoring normal sleep patterns by activating the thalamic reticular nucleus with chemogenetics reduced the accumulation of amyloid-beta plaques in the brains.

Featured Genetics Neuroscience Psychology

·July 5, 2021·6 min read

Common Mechanism Underlies Some Behavioral Traits Seen in Autism and Schizophrenia

Certain genes that are mutated or missing in those with schizophrenia and autism cause similar dysfunction in neural networks within the thalamus.

This shows the neurons mapped in the TRN

Autism Featured Neuroscience

·July 22, 2020·6 min read

Mapping the Brain’s Sensory Gatekeeper

Mapping the thalamic reticular nucleus, researchers have identified two distinct subnetworks of neurons with different functions. Findings offer insight into more specific targets for therapeutics to alleviate some sensory, sleep, and attention symptoms associated with ASD and other disorders characterized by sensory hypersensitivity.

This is a drawing of a person blocking their ears

Auditory Neuroscience Autism Featured Neuroscience

·October 23, 2019·5 min read

Drug combination reverses hypersensitivity to noise

Summary: Treating mouse models of autism with modafinil and EBIO reduced hypersensitivity to noise. Source: MIT People with autism often...

This shows a cartoon of a woman trying to read with lots of distractions in the background

Featured Neuroscience

·June 12, 2019·5 min read

How we tune out distractions

A pathway linking the basal ganglia to the thalamus enhances sensory discrimination and is used to suppress 'background noise'. The pathway, which is controlled by the prefrontal cortex, selectively suppresses sensory input as it flows to the thalamus.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 2, 2018·4 min read

Where Brain Cells Get Their Information May Determine Their Roles in Diseases

Researchers have mapped the relationship of two types of neurons implicated in psychiatric and movement disorder. The findings could lead to new treatments for a range of disorders from depression to Parkinson's disease.

Illustration of a brain with balls inside all networked together.

Featured Neuroscience

·October 13, 2015·5 min read

How the Brain Controls Sleep

Researchers have discovered a brain circuit that can trigger small regions of the brain to fall asleep or become less alert, while the rest of the brain remains awake.