T cells

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T cells

·January 15, 2021·4 min read

T Cells Linked to Myelin Implicated in MS-Like Disease in Monkeys

Some of the T cell epitopes targeting myelin in monkeys were the same as those found in humans. Researchers say linking these specific cells opens the doors to developing antiviral therapies that could be useful to treat newly diagnosed cases of MS in humans. Read More

Featured Neuroscience

·September 14, 2020·5 min read

Immune System Affects Mind and Body

The immune molecule interleukin-17 (Il-17a) appears to influence vigilance and alertness in mouse models. Findings suggest the immune cell affects both brain function and behavior. Read More

This shows neurons in the developing brain

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·July 22, 2020·5 min read

New Role for White Blood Cells in the Developing Brain

When T helper cells are absent in the brain, microglia remain suspended between the fetal and adult developmental state. Mice lacking brain T cells showed changes in behavior and defective synaptic pruning. The study reveals the critical role T cells play in the development of the brain. Read More

Featured Neurology Neuroscience

·May 14, 2020·4 min read

Local inflammatory cells are characteristic for advanced multiple sclerosis

In late-stage multiple sclerosis, inflammatory cells no longer enter the brain via the bloodstream, but instead the cells arise in memory from local memory cells inside the brain. The findings suggest during the late phases of multiple sclerosis, the disease is occurring entirely inside the brain. Read More

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·May 5, 2020·4 min read

Recently recovered COVID-19 patients produce varying virus-specific antibodies

Recovered coronavirus patients show a wide range of immune responses following the infection, with about half from a current study showing sustained antibodies two weeks later. Results indicate which parts of the virus are most effective at triggering the immune responses. Read More

Featured Neuroscience

·May 2, 2020·5 min read

Temporarily suppressing immune system during early COVID-19 infection may prevent severe symptoms

A new mathematical model examined the immune response in patients with coronavirus. The findings suggest adaptive immune response may kick in before target immune cells are depleted, slowing the infection. The interaction of the innate and adaptive immune response may explain why some with coronavirus experience a second wave infection, appearing to get better before the symptoms return and get worse. Other studies have shown those who received immunosuppressants at the start of infection had a better clinical outcome than those who did not. Read More

Featured Genetics Neuroscience Psychology

·April 21, 2020·3 min read

Antibodies could provide new treatment for OCD

People with OCD have six times higher Immuno-moodulin (Imood) expression that those without the disorder. Blocking Imood with the aid of an antibody reduced OCD-like behaviors in mouse models within a couple of days following treatment. Read More

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·April 20, 2020·4 min read

Further evidence autoimmunity plays a role in Parkinson’s disease

T cells that react to alpha-synuclein are most abundant in the early stages of Parkinson's disease but tend to disappear as the disease progresses. Signs of autoimmunity can appear in Parkinson's patients up to ten years before a diagnosis of the neurodegenerative disease. The detection of T cell response could be an early biomarker for Parkinson's, long before the physical symptoms begin to manifest. Read More

Featured Genetics Neuroscience Open Neuroscience Articles

·March 12, 2020·4 min read

Researchers identify potential targets for immune response to COVID-19

Study provides first potential targets for effective immune responses against COVID-19. The findings provide essential information for vaccine design against SARS-CoV-2. Read More

Featured Genetics Neurology Neuroscience

·February 4, 2020·5 min read

Dietary interventions may slow onset of inflammatory and autoimmune disorders

Reducing dietary levels of methionine can slow the onset and progression of inflammatory and autoimmune diseases, such as multiple sclerosis, in those with high-risk factors. Read More

This is a drawing of a brain in a castle

Brain Cancer Featured Genetics Neurology Neuroscience

·January 15, 2020·3 min read

Scientists breach brain barriers to attack tumors

Introducing VEGF-C into the cerebrospinal fluid of mouse models of glioblastoma, researchers noted increased levels of T cell response to the cancerous tumors. When combined with immune system checkpoint inhibitors, the VEGF-C treatment significantly extended the life span of the mice with glioblastoma brain cancer. Read More

Featured Neurology Neuroscience

·January 8, 2020·4 min read

Gut microbes may improve stroke recovery

Microbiota-derived short-chain fatty acids (SCFA) modulate stroke recovery. The effect was mediated by circulating lymphocytes on microglia activation. The study reports SCFAs could be a potential therapeutic to improve post-stroke recovery. Read More

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