Immune cells invade aging brains, disrupt new nerve cell formation
Intrusive T cells have been discovered in the brain's neurogenic niches of older mice and humans. Findings suggest the T cells impair neurogenesis.... Read More...
T cells
Newly discovered immune cells at the frontline of HIV infection
A newly discovered subset of dendritic cells have been implicated in sexually transmitted HIV infection. The CD11c+ dendritic cells are found in human genital tissue at the epithelial level. They are the first immune cells to interact with the HIV virus. The cells directly transfer the virus to CD4 T cells, making them key drivers in HIV transmission.... Read More...
Is multiple sclerosis linked to childhood viral infections?
Exposure to viral infections in the brain during childhood has been linked to an increased risk of developing multiple sclerosis later in life. ... Read More...
Immune cells determine how fast certain tumors grow
Immune cells can accelerate the growth of cancerous tumors in mouse models of NF1.... Read More...
Probiotic-derived molecule may suppress fatal brain inflammation
Capsular polysaccharide A (PSA), an envelope molecule, may help to boost the immune system and protect against potentially fatal neuroinflammation associated with Herpes Simplex Encephalitis (HSE). Mice given PSA survived exposure to a lethal herpes simplex viral infection, while those not treated with the probiotic did not, despite both groups being treated with a common antiviral used to treat HSE.... Read More...
Unlocking the female bias in lupus
Disruptions in maintaining X chromosome inactivation of T cells may explain why women are more prone to developing SLE than males.... Read More...
How Sleep Helps to Fight Infection
Researchers report sleep can help immune cells attach to targets and help fight infection. The study reveals how sleep assists the body in fighting infections, whereas conditions like chronic stress can make the body more susceptible to illness.... Read More...
New Immune System Regulators Revealed
Using CRISPR gene editing, researchers mapped important genes for helping T helper cells. The findings could help generate new treatments to activate the immune system against infection and to attack tumor cells.... Read More...
A Single Faulty Gene Can Lead to Lupus
Researchers report defects in the Ets1 gene is linked to characteristics associated with systemic lupus erythematosus immune abnormalities.... Read More...
DNA Vaccine Reduces Both Toxic Proteins Linked to Alzheimer’s
A new DNA vaccine tested in mice significantly reduces tau and amyloid beta, two proteins implicated in Alzheimer's disease. The findings, researchers say, may pave the way for clinical trials in humans with the neurodegenerative disease.... Read More...
Nature of Immune Cells in Brain Discovered
Researchers have discovered how the nature of T cells help protect the brain from viruses. The findings shed light on the role the immune system plays in a number of neurodegenerative disorders.... Read More...
How Salt Can Trigger Inflammation in Multiple Sclerosis
A new study reports salt could be a possible trigger for inflammation in multiple sclerosis. Researchers report cells in a high salt environment show activation of the beta catenin/Wnt signaling pathway, a pathway previously implicated in disrupting regulatory T cells and triggering inflammation.... Read More...