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T cells

·October 1, 2024·4 min read

Early Immune Cell Changes May Predict Multiple Sclerosis Onset

A new study shows that CD8-positive T cells play a significant role in the early stages of multiple sclerosis (MS). By studying identical twins where one twin has MS and the other is asymptomatic, researchers found that CD8 T cells exhibit specific changes before symptoms arise, including increased migration and inflammation promotion.

Featured Genetics Neuroscience

·January 24, 2024·3 min read

T Cells May Be The Living Anti-Aging Elixir

Researchers found that T cells can be genetically reprogrammed to target and eliminate senescent cells, which contribute to aging-related diseases. By using CAR (chimeric antigen receptor) T cells in mice, they achieved significant health improvements including lower body weight, enhanced metabolism, and increased physical activity.

Featured Neuroscience

·November 3, 2023·6 min read

Exercise Superpower: Immune T Cells Boost Muscle Endurance

A study offers insights into how exercise may be connected to the immune system. Conducted in mice, it reveals that exertion-induced muscle inflammation triggers the action of inflammation-countering T cells, termed Tregs.

Featured Neurology Neuroscience

·August 25, 2023·5 min read

3D Model Reveals T Cell Role in Alzheimer’s Progression

Researchers developed a 3D cellular model to study the interactions between brain cells and immune cells in Alzheimer's disease. This new model, based on advanced microfluidic technology, demonstrates that specific immune cells, CT8+ T Cells, amplify Alzheimer's pathology when they infiltrate the brain.

Featured Neuroscience Psychology

·August 22, 2023·3 min read

Immune’s Surprise Role: Regulatory T Cells Impact Mood and Memory

Regulatory T cells (Tregs), usually tasked with immune system regulation, might also play a pivotal role in mood stabilization. Controlled by the transcription factor Foxp3, any decrease in its expression has been linked to major depressive disorders.

Featured Neurology Neuroscience

·February 15, 2023·4 min read

Multiple Sclerosis Discovery Could End Disease’s Chronic Inflammation

Blocking the activity of the reactor called the aryl hydrocarbon receptor in T cells resulted in both a decrease in inflammation and recovery in mouse models of multiple sclerosis.

Brain Cancer Featured Neuroscience

·December 11, 2022·4 min read

CAR-T-Cell Shows Promise in Patients With Lymphoma of the Brain and Spinal Cord in Early Trial

Axicabtagene ciloleucel (axi-cel), a form of CAR-T therapy appears to be safe and has encouraging signs of efficacy in treating both lymphoma of the brain and spinal cord injury.

Featured Neurology Neuroscience

·December 6, 2022·5 min read

Immunotherapy Eliminates Disease-Causing Cells in Multiple Sclerosis-Like Disease

CAR-T, a therapy generally used in the treatment of cancer, has been shown to eliminate unhealthy cells that trigger autoimmunity in mouse models of multiple-sclerosis.

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Featured Neurology Neuroscience Open Neuroscience Articles

·November 10, 2022·5 min read

Blood Stem Cell Transplant Could Reboot Immune System in Multiple Sclerosis Patients

80% of patients with multiple sclerosis remain disease-free for the long term following an autologous hematopoietic stem cell transplant.

Featured Genetics Neuroscience

·July 2, 2022·3 min read

Important Factors for Regulating the Body’s Immune Response

Researchers identified differences in isoforms that control Treg cells and how that affects the body's immune system response.

Featured Neuroscience

·March 22, 2022·3 min read

How Sugar Promotes Inflammation

Excessive glucose consumption directly promotes the pathological function of certain cells within the immune system. Calorie-reduced diets can have beneficial effects on the immune system and have autoimmune diseases.