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Stanford

·April 10, 2025·7 min read

Digital Mouse Brain Twin Offers New Window Into Neural Function

Researchers have created an AI-powered "digital twin" of the mouse visual cortex that can accurately simulate neural responses to visual input, including movies. Unlike earlier models, this digital twin generalizes beyond its training data, predicting neuron behavior and structure with remarkable accuracy.

Featured Genetics Neuroscience

·January 10, 2025·3 min read

How Fiber Fuels Anti-Cancer Gene Activity

Fiber digestion produces short-chain fatty acids like propionate and butyrate, which directly alter gene expression with anti-cancer effects, according to new research. The study found that these fatty acids influence genes involved in cell proliferation, differentiation, and apoptosis, key processes that control tumor growth. Researchers demonstrated these epigenetic changes in human cells and mouse models, highlighting fiber's systemic impact on health.

Featured Genetics Neuroscience

·December 21, 2024·8 min read

Rare Brain Cells Offer Clues to Aging and Rejuvenation

A study reveals how brain cell interactions influence aging, showing that rare cell types either accelerate or slow brain aging. Neural stem cells provide a rejuvenating effect on neighboring cells, while T cells drive aging through inflammation.

Featured Neuroscience

·November 25, 2024·8 min read

Dopamine and Serotonin Work in Opposition for Effective Learning

The interplay between dopamine and serotonin shapes behavior by creating a balance between reward-seeking and impulse control. A novel study demonstrated that both systems work in opposition but are essential for effective learning.

This shows a drawing of people watching a movie.

Featured Neuroscience Psychology

·October 22, 2024·6 min read

Watching Docudramas Boosts Empathy

A new study shows that after watching a docudrama about a wrongfully convicted prisoner, participants became more empathetic toward formerly incarcerated individuals and more supportive of criminal justice reform. The research revealed that personal stories portrayed in media can shift attitudes, encouraging viewers to reconsider their perceptions of marginalized groups.

Featured Genetics Neuroscience Psychology

·October 21, 2024·6 min read

AI Uncovers DNA Variants Linked to Psychiatric Disorders

Researchers developed an AI algorithm, ARC-SV, to detect complex structural variants in the human genome that previous methods missed. Analyzing over 4,000 genomes, researchers discovered thousands of complex variants, many affecting brain-related genes and linked to schizophrenia and bipolar disorder.

Featured Neuroscience

·October 2, 2024·6 min read

Targeting Glucose May Spark Neurogenesis

Neural stem cells, which create new neurons in the brain, become less active with age due to elevated glucose levels. Researchers found that by knocking out the glucose transporter gene GLUT4 in older mice, they could significantly increase the production of new neurons.

This shows a person holding a brain model.

Featured Neurology Neuroscience

·August 25, 2024·6 min read

Blocking a Brain Pathway Reverses Memory Loss in Alzheimer’s

Blocking the kynurenine pathway, a regulator of brain metabolism, can restore cognitive function in lab mice with Alzheimer’s disease. The pathway is overactivated in Alzheimer’s, disrupting glucose metabolism and starving neurons of energy. By inhibiting this pathway, researchers improved memory and brain plasticity in mice, offering hope for new treatments in humans. IDO1 inhibitors, currently in cancer trials, could be repurposed for Alzheimer’s treatment.

Featured Neuroscience Psychology

·June 17, 2024·7 min read

Six Types of Depression Identified

Researchers identified six depression subtypes through brain imaging and machine learning, revealing tailored treatment options. This breakthrough in precision psychiatry can improve treatment outcomes by matching patients with the most effective therapies based on their brain activity patterns.

Featured Neuroscience

·June 5, 2024·6 min read

Brain Plasticity’s Dark Side: New Insights into Addiction Mechanisms

Researchers discovered that adaptive myelination, a form of brain plasticity, contributes to drug addiction. A single morphine dose in mice triggered myelination in reward-related brain circuits, reinforcing drug-seeking behavior. Blocking this myelination prevented addiction, highlighting potential new treatment strategies.

Featured Neuroscience Psychology

·June 1, 2024·7 min read

Night Owls Beware: Late Bedtimes Harm Mental Health

Staying up late harms mental health regardless of one's natural sleep preference. Surveying nearly 75,000 adults, researchers discovered that both morning and night types who stayed up late had higher rates of mental disorders. Surprisingly, aligning with one's chronotype didn't matter—early bedtimes benefited everyone. The study suggests lights out by 1 a.m. for better mental health.

Featured Neuroscience Psychology

·April 12, 2024·10 min read

Key Brain Systems Implicated in Psychosis

Researchers provide new insights into the brain mechanisms behind psychosis. The research identified malfunctions in two critical brain systems—the "filter" and the "predictor" in individuals with psychosis.

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Stanford

Digital Mouse Brain Twin Offers New Window Into Neural Function

How Fiber Fuels Anti-Cancer Gene Activity

Rare Brain Cells Offer Clues to Aging and Rejuvenation

Dopamine and Serotonin Work in Opposition for Effective Learning

Watching Docudramas Boosts Empathy

AI Uncovers DNA Variants Linked to Psychiatric Disorders

Targeting Glucose May Spark Neurogenesis

Blocking a Brain Pathway Reverses Memory Loss in Alzheimer’s

Six Types of Depression Identified

Brain Plasticity’s Dark Side: New Insights into Addiction Mechanisms

Night Owls Beware: Late Bedtimes Harm Mental Health

Key Brain Systems Implicated in Psychosis

Reducing Visceral Fat Protects the Brain for Decades

Brain-First Hypothesis: Rethinking the Cambrian Explosion

Beyond the Gym: Why Your Brain Craves Creatine

Brain Switch for Action and Stress Identified

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