SPNs

·July 22, 2020·6 min read

Neural Vulnerability in Huntington’s Disease Tied to Release of Mitochondrial RNA

In both human cell and mouse models of Huntington's disease, RNA from mitochondria was misplaced within spiny projection neurons. The stray RNAs, which looked different to cells than RNA derived from the cell nucleus, trigger an immune reaction that can lead to striatal cell type vulnerability.

Featured Neuroscience

·June 23, 2018·4 min read

Researchers Solve the Case of the Missing Subplate

A new study reveals subplate cells may not simply disappear, they may, instead, be migrating to different levels of the cortex. In essence, subplate cells may become part of the cerebral cortex.