Researchers have successfully recorded neural activity in the human striatum.
In both human cell and mouse models of Huntington's disease, RNA from mitochondria was misplaced within spiny projection neurons. The stray RNAs, which looked different to cells than RNA derived from the cell nucleus, trigger an immune reaction that can lead to striatal cell type vulnerability.
A new study reveals subplate cells may not simply disappear, they may, instead, be migrating to different levels of the cortex. In essence, subplate cells may become part of the cerebral cortex.
Pauses in cholinergic interneuron activity could be a mechanism for controlling how animals respond to external stimuli, researchers report.