Copies for CAG and CTG triplets repeat themselves numerous times and disrupt normal gene sequences in some neurodegenerative diseases, a new study reports.
Researchers reveal how a repeating nucleotide sequence in the gene for a mutant protein may trigger Huntington's disease.
Researchers have discovered a new mutation responsible for spinocerebellar ataxia, an often fatal movement disorder.
A new study enhances understanding of the mechanisms vital to the regulation of the circadian system.
Researchers identified 21 proteins that specifically bind to a protein called ataxin-1. Twelve of these proteins enhance the misfolding of ataxin-1 and thus promote the formation of harmful protein aggregate structures, whereas nine of them prevent the misfolding.
Researchers from the Huck Institutes’ Center for Cellular Dynamics, led by Center director Melissa Rolls, have found that a neuroprotective...
