Researchers have discovered a new mutation responsible for spinocerebellar ataxia, an often fatal movement disorder.
Researchers from the Huck Institutes’ Center for Cellular Dynamics, led by Center director Melissa Rolls, have found that a neuroprotective...
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Researchers identified 21 proteins that specifically bind to a protein called ataxin-1. Twelve of these proteins enhance the misfolding of ataxin-1 and thus promote the formation of harmful protein aggregate structures, whereas nine of them prevent the misfolding.
Copies for CAG and CTG triplets repeat themselves numerous times and disrupt normal gene sequences in some neurodegenerative diseases, a new study reports.