serotonin

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serotonin

Featured Neuroscience Open Neuroscience Articles

·September 17, 2020·6 min read

How Psychedelics Bind to Key Serotonin Receptor

Researchers have uncovered the structure of psychedelic compounds when they actively bind to the 5-HT2A serotonin receptor on the surface of brain cells. The discovery could lead to the exploration of more precise compounds that offer the therapeutic effects of psychedelics for mental health disorders, but without the hallucinations. Read More

Autism Featured Neuroscience Open Neuroscience Articles

·September 2, 2020·6 min read

Guilt by Dissociation: The Role of Serotonin in Autism

SERT Ala56 impacts the structure of the SERT protein cells, increasing the activity of the transporter to abnormally high levels. The high-activity state results in the removal of too much serotonin from brain sites where serotonin is needed, both during development and in adults. Read More

Featured Open Neuroscience Articles Psychology

·August 14, 2020·6 min read

Study Uncovers the Molecular Events by Which Popular Antidepressants Work

Activity of the c-Fos gene begins the increase on the ninth day of exposure to antidepressants. By day 14, mice showed behavioral changes associated with SSRI use. This may explain why suicide rates drop after nine days of treatment, and symptoms of depression improve after three weeks. Read More

This shows the location of the amygdala in the brain

Featured Neuroscience Psychology

·July 10, 2020·5 min read

Amygdala Changes in Male Patients with Schizophrenia and Bipolar Disorder

Study uncovers DNA hypermethylation is responsible for reduced amygdala volume in male patients with schizophrenia and bipolar disorder. Read More

This shows a scary shadow and an anxious man

Featured Neuroscience Open Neuroscience Articles Psychology

·July 9, 2020·6 min read

How Fear Transforms into Anxiety

In anxiety, neural activity becomes elevated across many specific brain regions, and normal coordination between the networks becomes decreased. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·June 10, 2020·3 min read

Will lockdown loneliness make us loners?

Social preference in isolated zebrafish is caused by stress and anxiety, not observed anti-social patterns. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·June 1, 2020·4 min read

How ketamine combats depression

Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·May 15, 2020·5 min read

Countering the negative effects of a common antidepressant

The SSRI sertraline (Zoloft), if taken while pregnant, can result in birth defects caused by the drug damaging a cell's genetic information. Researchers report one potential way to counter the effect is with specific antioxidants. Read More

This shows a print out of the genetic findings from different brain regions

Featured Genetics Neuroscience Psychology

·May 11, 2020·1 min read

Why some people are more prone to anxiety

Increased levels of serotonin transporters in the amygdala may explain why some people are more prone to anxiety than others. Read More

Featured Neurology Neuroscience

·April 29, 2020·4 min read

Breastfeeding helps prevent mothers from developing diabetes after childbirth

Women who breastfeed have a reduced risk of developing diabetes, a new study reports. In mouse models, lactation improved glucose tolerance and increased beta-cell mass three weeks post-delivery. Prolactin produced as a result of lactation induced serotonin production of beta cells. Findings suggest serotonin mediates the long-term beneficial effects of lactation of female metabolic health by increasing beta-cell proliferation and reducing oxidative stress in beta-cells. Read More

Featured Neuroscience Psychology

·April 23, 2020·4 min read

A biological mechanism for depression

People with depression have increased amounts of tubulin in lipid rafts compared to those without the disorder. Read More

Featured Neuroscience Open Neuroscience Articles

·April 16, 2020·4 min read

Neuronal and neurotransmitter systems dynamic coupling explains the effects of psilocybin

Computational simulations reveal the integration of both neuronal and neurotransmitter systems at a whole-brain level is vital to fully understand the effects of psilocybin on brain activity. Read More

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