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serotonin

·May 15, 2023·6 min read

Decoding Serotonin: A Comprehensive Study on Its Impact on Brain and Behavior

Researchers conducted a detailed study on serotonin, a key molecule in influencing mood and behavior, tracing its impact from the molecular level to the brain's overall functioning. Using the simple animal model of C. elegans, the team was able to map serotonin's effects across the entire brain, giving a comprehensive view of its behavioral influence.

Brain Cancer Featured Neuroscience

·March 22, 2023·3 min read

Turn Up Your Favorite Song to Improve Medication Efficacy

Listening to music may help boost the beneficial effects of medicine while helping to reduce some of the side effects. Cancer patients who listened to their favorite music while experiencing chemotherapy-related nausea reported a decrease in nausea severity and stress.

This shows a woman's head and a drawing of a brain

Featured Neuroscience Open Neuroscience Articles

·February 23, 2023·5 min read

Dynamic Expression of Brain Serotonin Receptors Across the Menstrual Cycle Provides Clues About Premenstrual Dysphoric Disorder

Roughly, 3 to 8% of women suffer from premenstrual dysphoric disorder (PMDD), a disorder that causes anxiety, depression, and mood swings during the menstruation cycle. PMDD appears to increase serotonin transporter density from the preovulation phase to the premenstrual cycle phase. The findings could aid in the development of new treatments for PMDD.

Featured Neuroscience Psychology

·February 16, 2023·3 min read

Receptor Location Matters for Psychedelic Drug Effects

Location bias may explain how psychedelic medications work. Researchers found that engaging serotonin 2A receptors inside neurons promotes the growth of new connections, but engaging the same receptor on the outside of a neuron does not. The findings may guide the development of new psychoplastogens to treat a range of disorders including depression and PTSD.

Featured Neuroscience Psychology

·February 8, 2023·6 min read

Why PTSD Patients Relive Highly Charged Fear Memories in Sleep

In people with PTSD, during REM sleep norepinephrine and serotonin levels remain high, reducing the brain's ability to inhibit fear-expression neurons through neural rhythms sent between the prefrontal cortex and amygdala. Those with PTSD require higher frequency rhythms to extinguish fear memories. Researchers say unlocking the higher frequencies via therapies could help to restore quality sleep in those with PTSD.

Featured Neuroscience Psychology

·January 23, 2023·5 min read

Study Explains Emotional ‘Blunting’ Caused by Common Antidepressants

SSRI antidepressants can make users less sensitive to rewards, resulting in emotional blunting many users experience. The findings provide new evidence for the role serotonin plays in reinforcement learning.

Featured Neurology Neuroscience Open Neuroscience Articles

·January 18, 2023·4 min read

How Serotonin Genes and SSRIs Can Contribute to Heart Valve Disease

Taking SSRIs and having the "long-long" serotonin SERT genetic variant lowers SERT activity in the mitral valve, leading to degenerative mitral regurgitation, one of the most common heart valve diseases.

This shows an outline of a mouse's head with the brain areas highlighted

Featured Neuroscience Open Neuroscience Articles Psychology

·December 28, 2022·4 min read

Good and Bad Feelings for Brain Stem Serotonin

A newly identified serotonin pathway that originates from the median raphe nucleus acts in opposition to the reward/aversion pathway in the nearby dorsal raphe nucleus. The findings could pave the way for the development of new treatments for major depression, addiction, and other disorders associated with serotonin.

This shows the brain probe in a jelly model of a brain

Featured Neuroscience Psychology

·December 19, 2022·5 min read

Soft Brain Probe Could Be a Boon for Depression Research

Researchers have developed a soft, implantable brain probe that can monitor serotonin and dopamine activity in real-time.

Featured Neuroscience

·December 19, 2022·4 min read

Serotonin 2C Receptor Associated With Obesity and Maladaptive Behavior

Mutations in the gene for the serotonin 2C receptor play a key role in obesity and dysfunctional behaviors in both human and animal models.

Featured Neuroscience Open Neuroscience Articles

·December 16, 2022·4 min read

Next Generation Genetically Encoded Fluorescent Sensors for Serotonin

A new fluorescent sensor allows researchers to track the activity of serotonin and helps visualize serotonin dynamics in the brain.

Featured Neuroscience Open Neuroscience Articles Psychology

·December 15, 2022·5 min read

New Support for the Notion of a Serotonin Deficit in Depression

Recent studies have suggested there is not enough evidence to support the serotonin hypothesis for depression. However, a new study shows direct evidence of disrupted serotonin release in the brains of those with depression.

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serotonin

Decoding Serotonin: A Comprehensive Study on Its Impact on Brain and Behavior

Turn Up Your Favorite Song to Improve Medication Efficacy

Dynamic Expression of Brain Serotonin Receptors Across the Menstrual Cycle Provides Clues About Premenstrual Dysphoric Disorder

Receptor Location Matters for Psychedelic Drug Effects

Why PTSD Patients Relive Highly Charged Fear Memories in Sleep

Study Explains Emotional ‘Blunting’ Caused by Common Antidepressants

How Serotonin Genes and SSRIs Can Contribute to Heart Valve Disease

Good and Bad Feelings for Brain Stem Serotonin

Soft Brain Probe Could Be a Boon for Depression Research

Serotonin 2C Receptor Associated With Obesity and Maladaptive Behavior

Next Generation Genetically Encoded Fluorescent Sensors for Serotonin

New Support for the Notion of a Serotonin Deficit in Depression

Shaping Young Minds: Neurodevelopment Interventions for Psychiatric Disorders

Ultra-Processed Foods: AI’s New Contribution to Nutrition Science

Aging Myelin: A New Perspective in Alzheimer’s Disease Progression

Promising Phase 2 Trial Results for Pembrolizumab in Metastatic Brain Cancer

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