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          serotonin

          This shows the outline of a man.
          FeaturedNeurosciencePsychology
          ·December 12, 2024·8 min read

          Gut Serotonin Plays Role in Depression and Mood

          Serotonin in the gut epithelium plays a critical role in modulating mood and may provide a safer target for treating depression and anxiety. In animal studies, increasing gut serotonin improved mood symptoms without causing digestive issues, unlike systemic antidepressant treatments.
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          This shows a woman and psychedelic swirls.
          FeaturedNeurosciencePsychology
          ·October 3, 2024·4 min read

          Psychedelics Reduce Anxiety Without Hallucinations

          New research has pinpointed the specific brain region and neuron type responsible for reducing anxiety using the psychedelic drug DOI, without triggering hallucinations. The study revealed that DOI targets serotonin2A receptors on parvalbumin-positive neurons in the ventral hippocampus, decreasing anxiety behaviors in animal models.
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          This shows the outline of a man.
          FeaturedNeuroscience
          ·September 28, 2024·5 min read

          Serotonin Levels Rise With Reward Anticipation

          Serotonin, known as the "happiness molecule," increases in anticipation of a reward and scales with the value of that reward. Using a biosensor called GRAB-serotonin, researchers measured serotonin in real time in mice as they received treats.
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          This shows guy bacteria.
          FeaturedNeurosciencePsychology
          ·September 23, 2024·4 min read

          Gut Microbiome Disruption Linked to Aggression

          Disruptions in the gut microbiome, especially due to early-life antibiotic use, lead to increased aggression in mice. Researchers transplanted microbiomes from infants exposed to antibiotics into mice and found a clear connection between altered gut bacteria and aggressive behavior.
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          This shows neurons.
          FeaturedNeuroscience
          ·September 21, 2024·5 min read

          Serotonin Receptor Dampens Visual Input to Enhance Internal Processes

          The 5-HT2A receptor in the brain reduces incoming visual information, allowing more space for internal thought processes. Researchers found that this receptor, when overactivated, suppresses sensory input, potentially explaining the effects of hallucinations from drugs like LSD.
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          This shows a depressed woman.
          FeaturedNeurosciencePsychology
          ·September 7, 2024·4 min read

          Role of Serotonin Release in Depression Uncovered

          Researchers developed a highly selective fluorescent probe to image serotonin in cells and animal models, shedding light on its role in depression. The study revealed that while serotonin levels in normal and “depressed” cells are similar, depressive cells release significantly less serotonin.
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          This shows a woman holding her head in her hands.
          FeaturedNeurosciencePsychology
          ·September 5, 2024·4 min read

          Observing Trauma Boosts Resilience Through Serotonin

          A new study reveals that observing others endure trauma can increase resilience and protect against depression. Researchers found that serotonin, released in the brain's habenula, plays a key role in this process, enhancing resilience by altering neuronal activity.
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          This shows neurons.
          FeaturedNeuroscience
          ·June 28, 2024·5 min read

          Serotonin 2C Receptor Key to Memory

          Researchers discovered the serotonin 2C receptor in the brain plays a crucial role in regulating memory in both humans and animal models. This breakthrough offers insights into conditions associated with memory loss, such as Alzheimer’s disease, and suggests new treatment pathways.
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          This shows a depressed woman.
          FeaturedNeurosciencePsychology
          ·June 6, 2024·4 min read

          How Antidepressants Treat Major Depression

          Researchers have developed a new framework explaining how antidepressants, like SSRIs, treat major depressive disorder (MDD) by restoring brain connectivity rather than correcting a serotonin imbalance. Their findings emphasize the continued importance of these medications despite shifting public opinion. This new understanding could improve patient-clinician conversations about depression treatment.
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          This shows a brain.
          FeaturedNeuroscience
          ·May 31, 2024·5 min read

          Activating Brain’s Serotonin Center Alters Behavior and Motivation

          Stimulating the brain's serotonin center, the dorsal raphe nucleus (DRN), activates areas responsible for behavior and motivation. This discovery, using opto-functional MRI in awake mice, highlights serotonin's significant role in cognitive functions. The study offers insights into how serotonin influences behavior and mood regulation.
          Read More
          This shows a person siting on a hill.
          FeaturedNeuroscience
          ·May 24, 2024·5 min read

          Serotonin Affects Behavior and Motivation

          A new study reveals how activating the brain's serotonin center affects behavior and motivation in awake mice. Using optogenetics and high-field MRI, researchers found that stimulating serotonin neurons in the dorsal raphe nucleus (DRN) activates the cerebral cortex and basal ganglia, critical areas for cognitive functions.
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          This shows a head and pills.
          FeaturedNeurosciencePsychology
          ·May 8, 2024·5 min read

          Psychedelics Activate Serotonin to Produce Antidepressant Effect

          A new study advanced our understanding of how psychedelic drugs activate serotonin receptors to offer potential treatments for neuropsychiatric disorders. The identifies the interaction of psychedelics like LSD and psilocybin with the serotonin receptor 5-HT1A, which is pivotal in their therapeutic effects.
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          This shows a brain.

          Side of Parkinson’s Onset Shapes Cognitive and Emotional Decline

          This shows two brains.

          Timing of Prozac Treatment Shapes Lasting Mood, Brain Changes

          This shows a person holding his heart.

          Emotional Neglect in Childhood Undermines Trust in One’s Own Body

          This shows astrocytes.

          Astrocytes in Obesity: Brain Cells That Control Metabolism & Cognition

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