Alterations associated with aging and cellular senescence may be linked to a decrease in cell proliferation, while cancer shifts towards increased cell division. The study challenges the traditional view that cancer risks increase as we age, finding the aging process may suppress the development of cancer.
According to researchers, obese mice have increased levels of senescent cells in their brains, and these cells contribute to anxiety. Using senolytics to clear the cells helps to reduce anxiety related behaviors.
Researchers report helping the immune system clear away old senescent cells in aging mice helped to restore youthful characteristics. The findings could have implications for reversing the effects of aging in humans.
Researchers report senescent, or Zombie, cells accumulate in certain neurons prior to cognitive loss. By preventing accumulation of these cells, researchers were able to diminish apoptosis, memory loss and tau aggregation.
A new study reports researchers have identified a possible new avenue for treating Parkinson's symptoms and neuropathology. Clearing senescent astrocytes appears to help prevent sporadic versions of the disease triggered by exposure to pesticides.
Removing senescent cells may help to reverse some of the signs of aging, researchers report.