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          senescent cells

          This shows a mouse fetus and a brain.
          FeaturedGeneticsNeuroscience
          ·June 16, 2026·10 min read

          Senescent Cells Are Essential for Building the Brain’s Barriers

          Cellular senescence is required for the proper construction of the brain's protective barrier systems.
          Read More
          This shows the outline of a head
          FeaturedGeneticsNeuroscience
          ·October 16, 2022·5 min read

          Scientists Reappraise the Role of ‘Zombie’ Cells That Anti-aging Medicine Has Sought to Eliminate

          Some senescent (zombie) cells are embedded in young, healthy tissue and promote normal repair from damage, researchers say.
          Read More
          This shows the zombie cells
          FeaturedGeneticsNeuroscience
          ·July 1, 2022·5 min read

          Researchers Uncover New Pathway for Accumulation of Age-Promoting ‘Zombie Cells’

          Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.
          Read More
          This shows a hippocampal slice
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·January 20, 2022·6 min read

          Old Neurons Can Block Neurogenesis in Mice

          Hippocampal neurogenesis and cognitive function were improved in aging mice by destroying senescent cells in the aging stem cell niche.
          Read More
          This shows an older lady with her hands crossed on her knees
          Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·September 27, 2019·3 min read

          Study finds age hinders cancer development

          Alterations associated with aging and cellular senescence may be linked to a decrease in cell proliferation, while cancer shifts towards increased cell division. The study challenges the traditional view that cancer risks increase as we age, finding the aging process may suppress the development of cancer.
          Read More
          This shows a cell
          FeaturedGeneticsNeuroscienceNeuroscience Videos
          ·July 25, 2019·4 min read

          Researchers discover new cause of cell aging

          Findings have applications for senolyics, the development of drugs that could eliminate aging cells.
          Read More
          diagram of mice
          FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology
          ·January 3, 2019·4 min read

          Obese Mice Lose Anxiety When ‘Zombie Cells’ Exit the Brain

          According to researchers, obese mice have increased levels of senescent cells in their brains, and these cells contribute to anxiety. Using senolytics to clear the cells helps to reduce anxiety related behaviors.
          Read More
          immune cells and organ slices
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·December 31, 2018·3 min read

          The Immune System’s Fountain of Youth

          Researchers report helping the immune system clear away old senescent cells in aging mice helped to restore youthful characteristics. The findings could have implications for reversing the effects of aging in humans.
          Read More
          a cell
          FeaturedGeneticsNeuroscience
          ·October 2, 2018·4 min read

          It Is Possible to Reverse Damage Caused by Aging

          A new study reports it is possible to reverse the effects of aging, at least on a cellular level. Researchers say molecules called senolytics can reverse the impact of aged, senescent cells.
          Read More
          neurons
          FeaturedNeurologyNeuroscience
          ·September 19, 2018·4 min read

          Zombie Cells Found in Mouse Brains Prior To Cognitive Loss

          Researchers report senescent, or Zombie, cells accumulate in certain neurons prior to cognitive loss. By preventing accumulation of these cells, researchers were able to diminish apoptosis, memory loss and tau aggregation.
          Read More
          astrocytes
          FeaturedNeurology
          ·January 23, 2018·3 min read

          New Therapeutic Avenue for Parkinson’s

          A new study reports researchers have identified a possible new avenue for treating Parkinson's symptoms and neuropathology. Clearing senescent astrocytes appears to help prevent sporadic versions of the disease triggered by exposure to pesticides.
          Read More
          Image shows rats.
          FeaturedGenetics
          ·June 9, 2017·5 min read

          Removal of Aging Cells Could Extend Human Life

          Researchers report a targeted removal of senescent cells could delay the onset of age related pathologies.
          Read More
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          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

          Alternative graphical abstract is shown.

          Study of Brain Immune Cells Reveals New Clues to Alzheimer’s Disease Progression

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