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senescent cells

·October 16, 2022·5 min read

Scientists Reappraise the Role of ‘Zombie’ Cells That Anti-aging Medicine Has Sought to Eliminate

Some senescent (zombie) cells are embedded in young, healthy tissue and promote normal repair from damage, researchers say.

Featured Genetics Neuroscience

·July 1, 2022·5 min read

Researchers Uncover New Pathway for Accumulation of Age-Promoting ‘Zombie Cells’

Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.

Featured Genetics Neuroscience Open Neuroscience Articles

·January 20, 2022·6 min read

Old Neurons Can Block Neurogenesis in Mice

Hippocampal neurogenesis and cognitive function were improved in aging mice by destroying senescent cells in the aging stem cell niche.

This shows an older lady with her hands crossed on her knees

Brain Cancer Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 27, 2019·3 min read

Study finds age hinders cancer development

Alterations associated with aging and cellular senescence may be linked to a decrease in cell proliferation, while cancer shifts towards increased cell division. The study challenges the traditional view that cancer risks increase as we age, finding the aging process may suppress the development of cancer.

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·July 25, 2019·4 min read

Researchers discover new cause of cell aging

Findings have applications for senolyics, the development of drugs that could eliminate aging cells.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·January 3, 2019·4 min read

Obese Mice Lose Anxiety When ‘Zombie Cells’ Exit the Brain

According to researchers, obese mice have increased levels of senescent cells in their brains, and these cells contribute to anxiety. Using senolytics to clear the cells helps to reduce anxiety related behaviors.

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·December 31, 2018·3 min read

The Immune System’s Fountain of Youth

Researchers report helping the immune system clear away old senescent cells in aging mice helped to restore youthful characteristics. The findings could have implications for reversing the effects of aging in humans.

Featured Genetics Neuroscience

·October 2, 2018·4 min read

It Is Possible to Reverse Damage Caused by Aging

A new study reports it is possible to reverse the effects of aging, at least on a cellular level. Researchers say molecules called senolytics can reverse the impact of aged, senescent cells.

Featured Neurology Neuroscience

·September 19, 2018·4 min read

Zombie Cells Found in Mouse Brains Prior To Cognitive Loss

Researchers report senescent, or Zombie, cells accumulate in certain neurons prior to cognitive loss. By preventing accumulation of these cells, researchers were able to diminish apoptosis, memory loss and tau aggregation.

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·January 23, 2018·3 min read

New Therapeutic Avenue for Parkinson’s

A new study reports researchers have identified a possible new avenue for treating Parkinson's symptoms and neuropathology. Clearing senescent astrocytes appears to help prevent sporadic versions of the disease triggered by exposure to pesticides.