Glioblastoma brain cancer originates from a pool of stem cells that can be a significant distance away from where the tumor eventually forms. Read More
An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD. Read More
Reducing levels of the Alzheimer's related Tau protein prevents autism-like behaviors in mouse models. Tau reduction also prevented seizures in the animals. Read More
Postmortem study reveals those with ASD have cellular abnormalities that impair the production of myelin. Read More
Copy number variants may act as genetic modifiers that influence the risk of autism and developmental delay versus cancer risk in people with PTEN mutations. Read More
Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors. Read More
A metabolite has been identified that can predict whether people with PTEN mutations will develop cancer or ASD. Read More
Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies. Read More
PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals. Read More
Researchers will present their latest findings regarding genes associated with autism spectrum disorder in an upcoming meeting. Read More
Targeting the gene WWP1 with indole-3-carbinol, a compound found in broccoli and other cruciferous vegetables, suppressed tumor growth in animal models of cancer. Read More
A new study sheds light on how our brains are constructed. Researchers say the study reveals how the balance of excitatory and inhibitory neurons in the cerebral cortex has remained constant over mammalian evolution. Read More
