New therapeutic strategy may help reverse autism behavioral abnormalities
Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors.... Read More...
PTEN
Predicting cancer versus autism risk in PTEN patients
A metabolite has been identified that can predict whether people with PTEN mutations will develop cancer or ASD.... Read More...
Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes
Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.... Read More...
Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study
PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.... Read More...
New approaches to study the genetics of autism may lead to new therapies
Researchers will present their latest findings regarding genes associated with autism spectrum disorder in an upcoming meeting.... Read More...
Natural Compound Found in Broccoli Reawakens the Function of Potent Tumor Suppressor
Targeting the gene WWP1 with indole-3-carbinol, a compound found in broccoli and other cruciferous vegetables, suppressed tumor growth in animal models of cancer.... Read More...
How to Build a Brain
A new study sheds light on how our brains are constructed. Researchers say the study reveals how the balance of excitatory and inhibitory neurons in the cerebral cortex has remained constant over mammalian evolution.... Read More...
Gene Combinations That Cause Glioblastoma Brain Cancer Identified
CRISPR technology and advanced screening techniques allow researchers to comb through over 1500 genetic combinations to find multiple drivers of glioblastoma brain cancer. ... Read More...
Neurons That Regenerate and Neurons That Die
Findings could pave the way for developing new treatments to restore vision and repair retinal damage.... Read More...
Scientists Engineer Gene Pathway to Grow Brain Organoids With Surface Folding
Findings could help to identify cells affected by Zika virus, researchers report.... Read More...
Researchers Discover Clues to Altered Brain Wiring in Autism
Mutations in PTEN affect the assembly of connections between two brain areas important for the processing of social cues, researchers report. ... Read More...
Protection Against Parkinson’s Disease May Begin in the Gut
Researchers report cells located in the gut spark an immune response that protects neurons against damage connected to Parkinson's.... Read More...