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psychosis

·April 14, 2025·5 min read

LSD-Inspired Drug Reverses Psychosis Brain Damage Without Hallucinations

A new LSD-derived compound called JRT shows promise for treating schizophrenia and other brain disorders without inducing hallucinations. Developed by researchers who altered just two atoms in LSD’s structure, JRT maintains the psychedelic’s neuroplastic effects while avoiding its psychosis-linked risks.

Featured Neuroscience Psychology

·April 12, 2025·9 min read

Delusions Often Appear Before Hallucinations in Early Psychosis

A new study has found that delusions typically emerge before hallucinations in individuals at high risk for psychosis, overturning a long-standing belief that hallucinations drive delusional thinking. By analyzing symptom progression across three large cohorts, researchers consistently observed that delusions were the earliest symptom, reappearing even before hallucinations during relapses.

Featured Neuroscience Psychology

·April 9, 2025·5 min read

Elevated Dopamine in Cannabis Users May Explain Psychosis Risk

New research reveals that people with cannabis use disorder (CUD) have elevated dopamine levels in a brain region associated with psychosis, such as schizophrenia. This may help explain why frequent cannabis use can increase the risk of hallucinations and delusions.

Featured Neuroscience Psychology

·January 8, 2025·4 min read

Early Reproductive Aging Alters Brain Connectivity, Emotional Health

Research shows that accelerated reproductive ageing in females, such as early puberty or menopause, is linked to increased mental health risks at different life stages. Adolescents experiencing early puberty displayed unstable brain connectivity in regions tied to psychosis vulnerability, while middle-aged women with early menopause showed patterns linked to depression.

Featured Neuroscience Psychology Visual Neuroscience

·December 18, 2024·5 min read

Study Ties Visual Errors to Paranoid Beliefs

A new study suggests complex beliefs like paranoia may have roots in visual misperception. Participants prone to paranoia or teleological thinking were more likely to wrongly identify one moving dot as chasing another in a visual task.

Featured Genetics Neuroscience Psychology

·December 6, 2024·6 min read

Psychosis Risk Tied to Heavy Cannabis Use and Genetic Factors

Heavy cannabis use and genetic risk for schizophrenia independently contribute to the likelihood of developing psychosis. Researchers used two large datasets to analyze the relationship between cannabis use, schizophrenia polygenic risk scores (PRS), and psychosis.

Featured Neuroscience Psychology

·November 26, 2024·4 min read

Brain Biomarker Could Predict Psychosis Before Symptoms Emerge

Researchers have identified a brain biomarker that may predict psychosis onset before symptoms appear, enabling earlier interventions and personalized care. MRI scans revealed abnormal connectivity patterns in sensory brain networks, with weaker connections between sensory regions and stronger connections to the thalamus.

Featured Neuroscience Psychology

·November 21, 2024·4 min read

Cannabis Worsens Brain Connectivity Deficits in Psychosis Risk

Young adults at risk of psychosis show reduced synaptic density, a critical brain connectivity deficit that cannabis use appears to exacerbate, according to new research. The study revealed lower synaptic density linked to social withdrawal and motivational deficits, symptoms poorly addressed by current medications.

This shows the outline of people and brains.

Featured Neuroscience Psychology

·November 13, 2024·4 min read

Metabolic Pathways Link Cannabis to Psychosis in Teens

A study investigated how cannabis use influences metabolomic patterns linked to psychotic-like experiences in adolescents. Blood samples revealed that non-cannabis users showed inflammatory metabolic changes associated with hallucinations, while cannabis users exhibited shifts in energy-related metabolites tied to brain ketogenesis. These findings suggest that cannabis use may trigger distinct molecular pathways in psychotic-like experiences.

Featured Genetics Neuroscience Psychology

·October 28, 2024·5 min read

Childhood Attention Problems and Genes Linked to Psychosis Risk

Childhood attention issues, coupled with genetic predispositions, increase the likelihood of experiencing psychotic-like symptoms in adolescence. By analyzing data from 10,000 youths, researchers discovered that variability in attention spans partially explains how genetic risk factors translate into psychotic-like symptoms.

Featured Genetics Neuroscience Psychology

·October 17, 2024·6 min read

Cannabis Leaves Molecular Marks on DNA Linked to Psychosis

Frequent use of high-potency cannabis leaves unique molecular marks on DNA, particularly affecting genes related to energy and immune function. Researchers found that DNA methylation—an epigenetic modification—differed between frequent cannabis users who had experienced psychosis and those who had not, suggesting a possible genetic link to psychosis risk.

Featured Neuroscience Psychology Visual Neuroscience

·October 1, 2024·5 min read

Reduced Brain Response to Visual Cues Linked to Psychosis in Parkinson’s

People with Parkinson's disease (PD) who experience visual hallucinations have reduced brain responses to unexpected visual changes, a marker known as visual mismatch negativity (vMMN). Using EEG, researchers compared brain activity in PD patients with and without hallucinations and discovered that those with hallucinations showed weaker vMMN signals.

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psychosis

LSD-Inspired Drug Reverses Psychosis Brain Damage Without Hallucinations

Delusions Often Appear Before Hallucinations in Early Psychosis

Elevated Dopamine in Cannabis Users May Explain Psychosis Risk

Early Reproductive Aging Alters Brain Connectivity, Emotional Health

Study Ties Visual Errors to Paranoid Beliefs

Psychosis Risk Tied to Heavy Cannabis Use and Genetic Factors

Brain Biomarker Could Predict Psychosis Before Symptoms Emerge

Cannabis Worsens Brain Connectivity Deficits in Psychosis Risk

Metabolic Pathways Link Cannabis to Psychosis in Teens

Childhood Attention Problems and Genes Linked to Psychosis Risk

Cannabis Leaves Molecular Marks on DNA Linked to Psychosis

Reduced Brain Response to Visual Cues Linked to Psychosis in Parkinson’s

The Placenta May Decide Autism Vulnerability

Imaging Index Links Blood Flow to Cellular Architecture

Nighttime Light Exposure Linked to Sleep Loss in Schizophrenia

Eye-Blink Rate Predicts Cognitive Flexibility in Preschoolers

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