Inducing hallucinations using visual stimuli in a lab setting enables more objective and reliable testing.
Study adds to the growing evidence Bartonella infection is associated with neuropsychological symptoms in addition to dermatological symptoms.
White matter connectivity does not directly induce psychosis, but may affect symptoms of psychosis through its effect on the consciousness threshold.
Genetic risk score for bipolar disorder is associated with an increased risk of developing bipolar symptoms. The genetic risk factor for schizophrenia is linked to an increased risk of those with depression developing psychosis.
Using data from MRI brain scan images, machine learning was 85% accurate at providing a diagnosis of psychiatric disorders that matched psychiatrists' assessments. The algorithm could also distinguish between patients with ASD, schizophrenia, risk factors for psychosis, and those with no history of mental health problems.
Depression treatments, including antidepressants, may be effective first-line treatments for psychosis if used in combination with established interventions for the condition.
Pimavanserin substantially reduces symptoms of psychosis and relapse risk for people living with dementia.
Coronavirus infection can lead to an array of neurological complications, including delirium, stroke, and a rare, often fatal neuroinflammatory condition called ADEM. The neurological complications did not always correlate with the severity of respiratory symptoms. In some patients, brain inflammation was likely caused by an immune response to COVID-19, suggesting the neurological damage may be a result of immune system activation rather than the virus itself.
Auditory hallucinations, a common feature of psychosis and schizophrenia, may be the result of increased connectivity between sensory and language processing areas in the brain.
Suicide rates for those with schizophrenia spectrum disorders (SSD) are 170 times higher than the general population. Suicide risk is predicted by key factors including age, evidence of mood disorders and hospitalization. An increased risk of suicidal behavior in those with SSD occurrs within the first five years following diagnosis.
Patients with psychosis who have higher levels of an antioxidant called glutathione responded more quickly to medications and had improved outcomes. Researchers estimate a 10% increase in antioxidants could lead to reduced time spent in hospital for those with psychosis.
NMDA receptor hypofunction is involved in the reduction of sleep spindles and delta oscillations, which appear in the brain during deep natural sleep. Findings confirm the role NMDA receptors play in sleep disorders that accompany psychotic states.