Decreased activation of the LEF1 gene is more common in bipolar patients who do not respond to lithium. Read More
As with other psychedelics, salvinorin A increased activity across the brain. However, salvinorin A use resulted in more random and disconnected signaling in the default mode network, a brain network associated with relaxing and daydreaming. Read More
With the risk of potential for abuse, some new fast-acting antidepressants, like Ketamine, may not be a magic "cure-all" for depression. Read More
A single dose of psychedelic treatments can help alleviate symptoms of depression, stress, and trauma in those who have experienced racial injustice. Read More
Female rats exposed to vaporized cannabis for 30 days developed a blunted response to stress. The effect was not seen in male rats. Findings shed light on how chronic cannabis use affects males and females differently. Read More
4E-BPs proteins are key to unlocking ketamine's antidepressant effects. When 4E-BPs are absent in neurons, ketamine can not produce its antidepressant effect. Read More
Schizophrenia may, in part, be caused by immune system dysfunction, a new study reports. Treatment with Methotrexate, a drug commonly prescribed for autoimmune disorders like R.A, produced positive effects against some prominent schizophrenia symptoms. Read More
Study reveals a link between people with depression who are prescribed newer antipsychotic medications and higher mortality risk. Read More
None of the 41 most commonly prescribed blood pressure medications increases the risk of depression. Nine medications that lower blood pressure were found to significantly lower depression risks. Read More
Focusing on genes associated with psychiatric and neurological disorders, and drugs approved for use in other diseases, a new AI system can increase the effectiveness of drug repurposing. Read More
Placebos reduce biomarkers in the brain of emotional distress, even when a patient knows they are taking one. Read More
Patients with psychosis who have higher levels of an antioxidant called glutathione responded more quickly to medications and had improved outcomes. Researchers estimate a 10% increase in antioxidants could lead to reduced time spent in hospital for those with psychosis. Read More
