Latest

psychopharmacology

·October 27, 2025·4 min read

Psychedelics May Rewire Memory Circuits Key to Mental Health

New research suggests that psychedelic drugs may work by strengthening specific brain connections linked to memory and cognition. Scientists found that under psychedelic exposure, neurons in the claustrum—a region dense with psychedelic-sensitive receptors—intensified their communication with the anterior cingulate cortex, a region involved in mood and psychiatric disorders.

Featured Neuroscience Psychology

·October 22, 2025·8 min read

Ketamine Fails to Outperform Placebo in Major Depression Trial

A large randomized and blinded clinical trial has found no additional benefit of repeated ketamine infusions over standard inpatient care for treating major depression. The study compared ketamine with a psychoactive placebo and found no meaningful differences in objective or self-reported depression scores, cognition, or quality of life.

This shows a woman, hearts, a brain, and brain waves.

Featured Neuroscience Psychology

·October 13, 2025·6 min read

EEG Test May Reveal Who Loses Libido on Antidepressants

A new study reveals that serotonin levels in the brain, measured using a simple EEG-based test, can predict who will experience sexual side effects from SSRI antidepressants. Researchers found that people with higher serotonin activity before treatment were significantly more likely to have difficulty reaching orgasm during antidepressant use.

Featured Neurology Neuroscience Pain Psychology

·October 2, 2025·6 min read

Psilocybin Rewire Brain Circuits Tied to Pain and Mood

New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site of injury. In mouse studies, a single dose provided pain relief and mood benefits lasting nearly two weeks by targeting the anterior cingulate cortex.

This shows a mom and child with a swirly background.

Featured Neuroscience Psychology

·September 30, 2025·7 min read

Psilocybin Worsens Postpartum Depression Symptoms

New research shows psilocybin, often studied as a treatment for mental health disorders, may worsen symptoms of postpartum depression in mice. Mothers given the drug showed more anxiety, avoidance of their pups, and lasting depressive-like behaviors.

Featured Neurology Neuroscience

·September 17, 2025·4 min read

Psychedelics Show Promise for Healing Concussions and Brain Injuries

Traumatic brain injuries, including concussions, affect nearly 69 million people worldwide each year, yet treatments remain scarce. A new review highlights the potential of psychedelics such as psilocybin and 5-MeO-DMT to reduce harmful inflammation and enhance neuroplasticity after brain injury.

Featured Neuroscience Open Neuroscience Articles Psychology

·August 27, 2025·3 min read

Cannabis Linked to Reduced Insomnia and Anxiety

A new study suggests cannabis-based medical products may help people with insomnia sleep better over the long term. Across 124 patients followed for up to 18 months, participants consistently reported improved sleep quality, less anxiety and depression, and a better overall quality of life.

This is a visual representation of the 5-HT1A serotonin receptor.

Featured Neuroscience Psychology

·August 2, 2025·6 min read

Fat Molecule May Control How You Feel Emotion

Scientists have uncovered how the brain’s 5-HT1A serotonin receptor—vital in mood regulation—functions at the molecular level. This receptor, a common target of antidepressants and psychedelics, prefers certain signaling pathways no matter the drug, but drugs can still vary in how strongly they activate them.

Featured Neuroscience Psychology

·July 19, 2025·6 min read

More Than Serotonin: How Psychedelics Engage the Whole Brain

Classical psychedelics like LSD, psilocybin, and mescaline are known for activating the 5-HT2A serotonin receptor, but a new study reveals their effects go far beyond. Researchers profiled 41 psychedelics against over 300 human receptors and found potent activity at serotonin, dopamine, and adrenergic sites.

Featured Genetics Neuroscience Psychology

·July 19, 2025·7 min read

Why Antidepressants Work Better for Some

A meta-analysis of gene expression data from humans and rodents reveals key biological pathways influencing response to the antidepressant fluoxetine. The study highlights the role of immune-related pathways, including toll-like receptor signaling, and neural signal transduction mechanisms in distinguishing responders from non-responders.

This shows supplement bottles on a shelf.

Featured Neuroscience Psychology

·July 16, 2025·7 min read

Do Supplements Work for Depression? Some Do, Study Says

A comprehensive review of over 23,000 studies identified 64 over-the-counter (OTC) supplements and herbal products evaluated in clinical trials for depression. St John’s Wort, saffron, probiotics, vitamin D, and omega-3s showed the strongest evidence, while others like lavender, zinc, and chamomile showed promise but need more research.

Featured Neuroscience Psychology

·July 10, 2025·7 min read

Most Antidepressant Users Don’t Face Severe Withdrawal

The largest review of antidepressant withdrawal studies shows most people don’t experience severe symptoms when stopping these medications. Analyzing data from nearly 18,000 participants, researchers found the most common withdrawal symptoms were mild, including dizziness, nausea, and nervousness.

1 2 3 … 39

psychopharmacology

Psychedelics May Rewire Memory Circuits Key to Mental Health

Ketamine Fails to Outperform Placebo in Major Depression Trial

EEG Test May Reveal Who Loses Libido on Antidepressants

Psilocybin Rewire Brain Circuits Tied to Pain and Mood

Psilocybin Worsens Postpartum Depression Symptoms

Psychedelics Show Promise for Healing Concussions and Brain Injuries

Cannabis Linked to Reduced Insomnia and Anxiety

Fat Molecule May Control How You Feel Emotion

More Than Serotonin: How Psychedelics Engage the Whole Brain

Why Antidepressants Work Better for Some

Do Supplements Work for Depression? Some Do, Study Says

Most Antidepressant Users Don’t Face Severe Withdrawal

$2 Saliva Test Could Help Detect Depression and Schizophrenia

How Chemotherapy Triggers Nerve Damage, and How to Stop It

Epigenetic Switch to Turn Memories On and Off Created

How Neurons Feel Force: Uncovering the Physics of Touch

Subscribe