Researchers have successfully created a synthetic version of a human prion, a protein associated with brain wasting diseases like sporadic Creutzfeldt-Jakob disease. The prions may help shed new light on, and provide treatment options, for those with CJD and other prion related diseases.
Researchers have detected a prion protein associated with CJD on the skin of almost two dozen people who died from the disease. The findings raise questions as to whether transmission of the disease via skin transplantation may be possible, and whether a simple skin test could detect the disease.
Researchers from the University of Plymouth have discovered the tole PrPC plays in the development of neurofibromatosis 2 tumors. According to the study, the prion protein is overproduced in schwannomas, compared with healthy Schwann cells. This overproduction is a result of Merlin deficiency and contributed to tumor growth in NF2 patients.
Researchers have uncovered the 3D structure of infectious prions.
A new study describes two distinct stages of prion disease.