A new study reports that both in solution and on supported membrane bilayers, multivalent interaction networks formed by major excitatory postsynaptic density scaffold proteins led to formation of PSD-like assemblies via phase separation.
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Researchers have created a new map that highlights protein associations through brain networks. The map is available through a software platform that allows users to visualize disease risk factors.
A new study provides insights into why mutations altering the SynGAP/PSD-95 interaction can contribute to various brain disorders.