Researchers have found a diverse array of illicit drugs, including cocaine and ketamine, along with pesticides and pharmaceutical chemicals in British freshwater shrimp. While the concentrations of chemicals were considered low, researchers state there is a concern for the potential environmental risk this may pose to wildlife.
Felodipine, a common hypertension medication, induces autophagy and clears aggregate-prone proteins associated with neurodegenerative diseases. The study reveals the drug clears mutant alpha-synuclein in the brains of mice at plasma concentrations to those seen in humans taking the medication. Felodipine appears to have some neuroprotective properties in mouse models of neurodegenerative diseases.
Cannabidiol may be able to bypass the blood-brain barrier to effectively deliver medications directly to the brain.
The formation of prefrontal cortex dendritic spine formation sustains the remission of depressive related symptoms and behaviors following ketamine treatment by restoring lost spines.
Classical music exposure paired with ibuprofen reduced response to inflammation pain by 93%, compared to exposure to the medication alone in mouse models of pain. For those exposed to just music, researchers report a 77% reduction in surgical pain.
Combining carboplatin, a common chemotherapy drug, with everolimus, a drug that blocks mTOR, is effective at inducing apoptosis and slowing tumor growth in patients with pediatric low-grade glioma brain cancer.
A new study reports combining antipsychotic medications could help to prevent relapse and hospitalization for those with schizophrenia. Combining aripiprazole and clozapine resulted in a 23% lower risk of re-hospitalization than with clozapine alone, researchers report.
Researchers have identified a small set of molecules that can convert glial cells into new neurons. The finding could help develop new treatments for Alzheimer's disease and brain injuries.
Researchers have developed a new antibiotic medication that appears to be safe and effective in treating clostridium difficile infection.