Parkinson's patients carrying mutations in PINK1 and Parkin genes have increased levels of circulating interleukin 6 and mitochondrial DNA. The findings strengthen a link between genetic risk factors from Parkinson's disease and inflammation.
A new study shows the loss of parkin sharply reduces the level of another protein which usually helps protect neurons from stress.
Researchers have determined the crystal structure of Parkin, a protein found in cells which, when matured, can lead to a hereditary form of Parkinson's disease.
Researchers identify a novel signaling pathway that activates the parkin gene and prevents stress induced neuronal cell death.
