Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.
Depression and cardiovascular disease appear to be closely related due to their links to inflammation and oxidative stress. Researchers say lowering the risks of cardiovascular disease can improve symptoms of depression.
A breakdown in regulatory mechanisms causes iron to build up in the brain during aging, increasing oxidative stress and increasing the risk of age-related cognitive decline, a new study reports.
Switching to a diet that includes more leafy greens, including spinach and kale, reduces inflammation and oxidative stress, and improved symptoms associated with chronic migraine.
Post-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell's mitochondria to fragment and increase oxidative stress. Reducing tau reversed the effect, decreasing oxidative stress and mitochondrial fragmentation.
A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers found oxidative stress through exposure to a Western diet increased the production of inflammatory cytokines confined to adipocytes and altered protein markers of memory and cognition in the hippocampus.
A single time vaping increases oxidative stress levels up to four times in non-smokers.
Study identifies specific chemical features of tau that may cause it to accumulate in the brain and trigger Alzheimer's disease.
From impairing nervous system function and changing bacterial communities in the microbiome to increasing oxidative stress and inflammation, researchers report on the ways in which exposure to chemical pollution harms the body.
An examination of brainstems from children and young adults constantly exposed to air pollution reveals markers of Alzheimer's disease, Parkinson's disease, and motor neuron disease. Findings suggest air pollution poses risks of serious neurological damage from an early age.