Brain organoids, or mini-brains, created from human stem cells appear to develop in much the same way as a human brain. The organoids follow an internal clock that guides their maturation in sync with the timeline for human brain development.
Study reveals the detailed internal anatomy of mini-brains for the first time.
SCOUT is a newly developed pipeline for clearing, labeling, 3D imaging, and analyzing cerebral organoids.
Organ-on-a-chip models reveal how different tissue contribute to inflammatory diseases such as ulcerative colitis.
Hailed by many as a breakthrough for neuroscience research, a new study reports brain-in-a-dish models may not be as useful as reported previously. The study reports instead of differentiating normally into the brain's distinctive cell types, cerebral organoids often express mixed genes normally found in different kinds of cells.
Machine learning is unable to tell the difference in brain activity between a lab-grown mini-brain and that of a preterm infant who has reached full-term.
Open sharing of scientific data and standard methods will allow researchers to collaborate on projects and accelerate understanding of neurodegenerative diseases.
Using induced pluripotent stem cells derived from patients with neurodegenerative disorders, researcher recreated the blood-brain barrier inside Organ-Chips.
Researchers have created an organoid of the thalamus, which they have fused with an organoid of the frontal cortex in order to study ASD, depression and other neuropsychiatric conditions.
Using human retinal tissue grown from stem cells, researchers shed light on how color vision develops. The study found thyroid hormones dictated whether the cells became blue, green or red photoreceptors.
With the first head transplant scheduled for 2018, many neuroscientists are skeptical the procedure will be a success. A new article questions if scientists, and the general population, will be ready for the procedure. What does it mean for the future of mankind?
Researchers use gene editing to generate aggressive glioblastoma multiforme brain tumors in the lab. The model, researchers say, could be used to track the progression of tumors and develop personalized therapies for patients.
