opioids

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The ‘inflammation’ of opioid use: Research correlates inflammation in the brain and gut to negative emotional state during opioid withdrawal

Inflammation caused by opioid use to both the brain and gut may exacerbate symptoms of negative emotions associated with withdrawal. Targeting the inflammation could help alleviate the negative experiences of opioid withdrawal and prevent dependence.... Read More...
This shows a person with pills in their hand

Common antidepressants interact with opioid med to lessen pain relief

SSRI antidepressants, such as Prozac and Paxil, interact with opioid medications to make them less effective at providing relief from chronic pain. Tramadol relies on activation of the CYP2D6 enzyme to control pain, but SSRIs inhibit this enzyme. Researchers suggest prescribing different classes of antidepressants which do not suppress the enzyme may benefit those in need of opioid medications. Alternatively, non-opioid pain killers should be considered for those who can not switch from SSRIs.... Read More...