Cancer patients with vitamin D deficiency under palliative care reported a decreased need for opioids to control pain and reduced symptoms of fatigue when given vitamin D supplementation.
Short-term opioid use increases positive emotional experiences by intensifying feelings of pleasure and weakening negative emotions. This, researchers say, could be a contributing factor for later opioid addiction. However, the long term use of opioids alters the reward system, diminishing the initial sensitivity and blunting emotions.
Researchers discover how pain fine tunes pain relief. The findings could help further understanding of pain and addiction to opioids.