A majority of Parkinson's patients report a diminished sense of smell, which starts to occur a number of years before the onset of other symptoms. Researchers are exploring whether scent-processing neurons which connect the nose to the brain may play a role in the development of Parkinson's disease.
The habenula relays external information, such as sight and smell, along with internal states associated with emotion and learning to brain regions that govern adaptive behaviors.
Women with postpartum depression report normal olfactory sensitivity, while those who are genetically predisposed to major depressive disorder have decreased olfactory sensitivity.
Following injury or damage, insulin plays a key role in the maturation and regeneration of immature olfactory sensory neurons.
People with a poor sense of smell are 50% more likely to be hospitalized for pneumonia than those with a good sense of smell.
Olfactory imprinting in infant mice has a direct impact on their social behaviors as adults.