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neuroplasticity

·February 8, 2025·7 min read

Mitochondria’s Role in Social Memory May Offer Clues to Brain Disorder

Researchers have identified a unique mitochondrial process in CA2 neurons that supports learning, memory, and social recognition. Mitochondria in different parts of these neurons vary in structure and function, with those at the outermost synapses relying on the mitochondrial calcium uniporter (MCU) for plasticity. Deleting the MCU gene disrupted this plasticity, highlighting its crucial role in maintaining neural connectivity.

Featured Neuroscience

·December 17, 2024·4 min read

Lab-Grown Neurons Mimic Brain Networks, Exhibit Neuroplasticity

Researchers have developed lab-grown neurons that behave more like real brain networks, advancing the study of learning and memory. Using microfluidic devices, the neurons formed diverse and functional networks, resembling those seen in living nervous systems.

Featured Neuroscience

·December 3, 2024·5 min read

Cannabis Impacts Brain Plasticity via Astrocyte Receptors

Researchers discovered that cannabis affects brain development by interacting with CB1 receptors on astrocytes, not just neurons. Using a mouse model, they showed that removing these receptors impaired the brain’s ability to adapt during critical periods of plasticity, particularly in the visual cortex.

Featured Genetics Neuroscience

·October 24, 2024·6 min read

Yamanaka Factors Can Reverse Neuronal Aging

Yamanaka factors can reverse aging in brain neurons, improving synaptic connections, metabolism, and protecting against neurodegenerative diseases like Alzheimer's. Researchers introduced the Yamanaka factors into neurons of adult mice, finding that this process rejuvenated the cells without negative side effects, even enhancing motor and social behaviors.

Featured Neuroscience

·October 10, 2024·3 min read

Bilingual Brains Build Stronger Connections

New research demonstrates that learning a second language enhances brain connectivity, particularly when started in childhood. Scientists found that bilingual individuals have more efficient communication between brain regions, notably between the cerebellum and left frontal cortex.

Featured Neuroscience

·October 9, 2024·6 min read

How Brains Learn Over Longer Timescales

Researchers have discovered a novel brain mechanism, behavioral timescale synaptic plasticity (BTSP), that enables neurons to encode information over seconds rather than milliseconds, aligning more closely with learning timescales. Previously, encoding models like Hebbian plasticity focused on neuron activity within mere milliseconds, but BTSP extends this window, allowing neurons to integrate information over seconds.

Featured Genetics Neuroscience

·September 27, 2024·3 min read

Enzyme Key to Brain Function and Synapse Health Discovered

A new study reveals that the absence of the TRMT10A enzyme disrupts tRNA levels, leading to impaired protein synthesis and brain function. Researchers found that mice lacking the Trmt10a gene had decreased levels of key tRNAs, which affected neuronal synapses and cognitive abilities.

This shows the outline of a woman and a brain.

Featured Neuroscience

·September 21, 2024·5 min read

Pregnancy Dramatically Reshapes the Brain

A new study provides the first detailed map of brain changes during pregnancy, showing significant neuroplasticity in adults. Researchers found a decrease in gray matter volume and a temporary increase in white matter in a pregnant brain.

Featured Neuroscience

·August 8, 2024·5 min read

Synaptic Quality Key to Age Related Memory Preservation

A recent study reveals that the quality, not the quantity, of synapses in the brain is crucial for preserving memory in older adults. Researchers found that larger dendritic spine head diameters in the temporal cortex correlate with better episodic memory performance, challenging the long-held belief that memory decline is primarily due to synapse loss.

Featured Genetics Neuroscience

·July 28, 2024·6 min read

Epigenetics Unlocks Secrets of Memory Formation

A new study reveals that the epigenetic state of neurons determines their role in memory formation. Neurons with open chromatin states are more likely to be recruited into memory traces, showing higher electrical activity during learning. Researchers demonstrated that manipulating these epigenetic states in mice can enhance or impair learning. This discovery shifts the focus from synaptic plasticity to nuclear processes, offering potential new avenues for treating cognitive disorders.

Featured Neuroscience

·June 5, 2024·6 min read

Brain Plasticity’s Dark Side: New Insights into Addiction Mechanisms

Researchers discovered that adaptive myelination, a form of brain plasticity, contributes to drug addiction. A single morphine dose in mice triggered myelination in reward-related brain circuits, reinforcing drug-seeking behavior. Blocking this myelination prevented addiction, highlighting potential new treatment strategies.

Featured Neuroscience

·May 29, 2024·8 min read

Third Thumb: Public Quickly Adapts to Controllable Extra Thumb

Researchers found that people easily learned to use a controllable, prosthetic "Third Thumb" for manipulating objects. The device, tested on a diverse group, enhances motor capabilities and shows promise for both productivity and aiding those with disabilities. The study highlights the importance of inclusive design in developing new technologies.